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The association of gene polymorphisms with the muscle fiber type composition. / Akhmetov, I. I.; Astratenkova, I. V.; Druzhevskaia, A. M.; Komkova, A. I.; Liubaeva, E. V.; Tarakin, P. P.; Shenkman, B. S.; Rogozkin, V. A.

в: Rossiǐskii fiziologicheskiǐ zhurnal imeni I.M. Sechenova / Rossiǐskaia akademiia nauk, Том 92, № 7, 01.07.2006, стр. 883-888.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Akhmetov, II, Astratenkova, IV, Druzhevskaia, AM, Komkova, AI, Liubaeva, EV, Tarakin, PP, Shenkman, BS & Rogozkin, VA 2006, 'The association of gene polymorphisms with the muscle fiber type composition', Rossiǐskii fiziologicheskiǐ zhurnal imeni I.M. Sechenova / Rossiǐskaia akademiia nauk, Том. 92, № 7, стр. 883-888.

APA

Akhmetov, I. I., Astratenkova, I. V., Druzhevskaia, A. M., Komkova, A. I., Liubaeva, E. V., Tarakin, P. P., Shenkman, B. S., & Rogozkin, V. A. (2006). The association of gene polymorphisms with the muscle fiber type composition. Rossiǐskii fiziologicheskiǐ zhurnal imeni I.M. Sechenova / Rossiǐskaia akademiia nauk, 92(7), 883-888.

Vancouver

Akhmetov II, Astratenkova IV, Druzhevskaia AM, Komkova AI, Liubaeva EV, Tarakin PP и пр. The association of gene polymorphisms with the muscle fiber type composition. Rossiǐskii fiziologicheskiǐ zhurnal imeni I.M. Sechenova / Rossiǐskaia akademiia nauk. 2006 Июль 1;92(7):883-888.

Author

Akhmetov, I. I. ; Astratenkova, I. V. ; Druzhevskaia, A. M. ; Komkova, A. I. ; Liubaeva, E. V. ; Tarakin, P. P. ; Shenkman, B. S. ; Rogozkin, V. A. / The association of gene polymorphisms with the muscle fiber type composition. в: Rossiǐskii fiziologicheskiǐ zhurnal imeni I.M. Sechenova / Rossiǐskaia akademiia nauk. 2006 ; Том 92, № 7. стр. 883-888.

BibTeX

@article{d981625ceba5447991c235c2ba0da7f9,
title = "The association of gene polymorphisms with the muscle fiber type composition",
abstract = "Muscle fiber composition of m. vastus lateralis has significant individual variability mainly depending on genetic factors. Present study shows analysis of association between polymorphisms of three muscle performance-related genes and muscle fiber type composition in 48 young healthy men. DNA was obtained from mouthwash samples by alkaline extraction. Polymorphism determination of PPARalpha, ACE and ACTN3 genes was performed using polymerase chain raction. Muscle fiber typing from m. vastus lateralis was performed using immunohistochemistry method. We found an association of increased frequency of intron 7 G allele of PPARalpha gene (93.9% vs 60.0%) and D allele of ACE gene (68.8% vs 34.4%) in the group with the highest proportion of slow-twitch fibers (56-70%) compared to the group with the lowest proportion (25-43%). Thus, PPARalpha and ACE genes can be considered as potential candidate genes for muscle fiber type determination.",
author = "Akhmetov, {I. I.} and Astratenkova, {I. V.} and Druzhevskaia, {A. M.} and Komkova, {A. I.} and Liubaeva, {E. V.} and Tarakin, {P. P.} and Shenkman, {B. S.} and Rogozkin, {V. A.}",
year = "2006",
month = jul,
day = "1",
language = "русский",
volume = "92",
pages = "883--888",
journal = "РОССИЙСКИЙ ФИЗИОЛОГИЧЕСКИЙ ЖУРНАЛ ИМ. И.М. СЕЧЕНОВА",
issn = "0869-8139",
publisher = "Издательство {"}Наука{"}",
number = "7",

}

RIS

TY - JOUR

T1 - The association of gene polymorphisms with the muscle fiber type composition

AU - Akhmetov, I. I.

AU - Astratenkova, I. V.

AU - Druzhevskaia, A. M.

AU - Komkova, A. I.

AU - Liubaeva, E. V.

AU - Tarakin, P. P.

AU - Shenkman, B. S.

AU - Rogozkin, V. A.

PY - 2006/7/1

Y1 - 2006/7/1

N2 - Muscle fiber composition of m. vastus lateralis has significant individual variability mainly depending on genetic factors. Present study shows analysis of association between polymorphisms of three muscle performance-related genes and muscle fiber type composition in 48 young healthy men. DNA was obtained from mouthwash samples by alkaline extraction. Polymorphism determination of PPARalpha, ACE and ACTN3 genes was performed using polymerase chain raction. Muscle fiber typing from m. vastus lateralis was performed using immunohistochemistry method. We found an association of increased frequency of intron 7 G allele of PPARalpha gene (93.9% vs 60.0%) and D allele of ACE gene (68.8% vs 34.4%) in the group with the highest proportion of slow-twitch fibers (56-70%) compared to the group with the lowest proportion (25-43%). Thus, PPARalpha and ACE genes can be considered as potential candidate genes for muscle fiber type determination.

AB - Muscle fiber composition of m. vastus lateralis has significant individual variability mainly depending on genetic factors. Present study shows analysis of association between polymorphisms of three muscle performance-related genes and muscle fiber type composition in 48 young healthy men. DNA was obtained from mouthwash samples by alkaline extraction. Polymorphism determination of PPARalpha, ACE and ACTN3 genes was performed using polymerase chain raction. Muscle fiber typing from m. vastus lateralis was performed using immunohistochemistry method. We found an association of increased frequency of intron 7 G allele of PPARalpha gene (93.9% vs 60.0%) and D allele of ACE gene (68.8% vs 34.4%) in the group with the highest proportion of slow-twitch fibers (56-70%) compared to the group with the lowest proportion (25-43%). Thus, PPARalpha and ACE genes can be considered as potential candidate genes for muscle fiber type determination.

UR - http://www.scopus.com/inward/record.url?scp=33947536657&partnerID=8YFLogxK

M3 - статья

C2 - 17300045

AN - SCOPUS:33947536657

VL - 92

SP - 883

EP - 888

JO - РОССИЙСКИЙ ФИЗИОЛОГИЧЕСКИЙ ЖУРНАЛ ИМ. И.М. СЕЧЕНОВА

JF - РОССИЙСКИЙ ФИЗИОЛОГИЧЕСКИЙ ЖУРНАЛ ИМ. И.М. СЕЧЕНОВА

SN - 0869-8139

IS - 7

ER -

ID: 42844130