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Testing anxiolytic drugs in the C57BL/6J mouse strain. / Kalueff, Allan V.; Nguyen, Michael.

в: Journal of Pharmacological and Toxicological Methods, Том 69, № 2, 2014, стр. 205-207.

Результаты исследований: Научные публикации в периодических изданиях › письмо/краткое сообщение › Рецензирование

Harvard

Kalueff, AV & Nguyen, M 2014, 'Testing anxiolytic drugs in the C57BL/6J mouse strain', Journal of Pharmacological and Toxicological Methods, Том. 69, № 2, стр. 205-207. https://doi.org/10.1016/j.vascn.2014.01.004

APA

Kalueff, A. V., & Nguyen, M. (2014). Testing anxiolytic drugs in the C57BL/6J mouse strain. Journal of Pharmacological and Toxicological Methods, 69(2), 205-207. https://doi.org/10.1016/j.vascn.2014.01.004

Vancouver

Kalueff AV, Nguyen M. Testing anxiolytic drugs in the C57BL/6J mouse strain. Journal of Pharmacological and Toxicological Methods. 2014;69(2):205-207. https://doi.org/10.1016/j.vascn.2014.01.004

Author

Kalueff, Allan V. ; Nguyen, Michael. / Testing anxiolytic drugs in the C57BL/6J mouse strain. в: Journal of Pharmacological and Toxicological Methods. 2014 ; Том 69, № 2. стр. 205-207.

BibTeX

@article{10627fbfebc1485c8cb2d1119302431a,
title = "Testing anxiolytic drugs in the C57BL/6J mouse strain",
abstract = "C57BL/6J mice are one of the most commonly used mouse strains in biobehavioral and psychopharmacological research. Prone to variance due to multiple environmental factors, animal neurophenotyping studies rely on using proper experimental protocols, study designs and well-established models and tests. Choosing the dose range for anxiolytic or anxiogenic drugs is key for obtaining valid testing results and correct data interpretation. Here we emphasize the importance of accurate dose selection in rodent anxiety paradigms for concluding whether the mouse strain used is {"}sensitive{"} and therefore appropriate for studying anxiety in selected behavioral tests. We also provide further argument in support of using the C57BL/6J mouse strain for testing anxiolytic and anxiogenic compounds.",
keywords = "Anxiety, Behavioral testing, Brain disorders, C57BL/6J mice",
author = "Kalueff, {Allan V.} and Michael Nguyen",
year = "2014",
doi = "10.1016/j.vascn.2014.01.004",
language = "English",
volume = "69",
pages = "205--207",
journal = "Journal of Pharmacological and Toxicological Methods",
issn = "1056-8719",
publisher = "Elsevier",
number = "2",

}

RIS

TY - JOUR

T1 - Testing anxiolytic drugs in the C57BL/6J mouse strain

AU - Kalueff, Allan V.

AU - Nguyen, Michael

PY - 2014

Y1 - 2014

N2 - C57BL/6J mice are one of the most commonly used mouse strains in biobehavioral and psychopharmacological research. Prone to variance due to multiple environmental factors, animal neurophenotyping studies rely on using proper experimental protocols, study designs and well-established models and tests. Choosing the dose range for anxiolytic or anxiogenic drugs is key for obtaining valid testing results and correct data interpretation. Here we emphasize the importance of accurate dose selection in rodent anxiety paradigms for concluding whether the mouse strain used is "sensitive" and therefore appropriate for studying anxiety in selected behavioral tests. We also provide further argument in support of using the C57BL/6J mouse strain for testing anxiolytic and anxiogenic compounds.

AB - C57BL/6J mice are one of the most commonly used mouse strains in biobehavioral and psychopharmacological research. Prone to variance due to multiple environmental factors, animal neurophenotyping studies rely on using proper experimental protocols, study designs and well-established models and tests. Choosing the dose range for anxiolytic or anxiogenic drugs is key for obtaining valid testing results and correct data interpretation. Here we emphasize the importance of accurate dose selection in rodent anxiety paradigms for concluding whether the mouse strain used is "sensitive" and therefore appropriate for studying anxiety in selected behavioral tests. We also provide further argument in support of using the C57BL/6J mouse strain for testing anxiolytic and anxiogenic compounds.

KW - Anxiety

KW - Behavioral testing

KW - Brain disorders

KW - C57BL/6J mice

UR - http://www.scopus.com/inward/record.url?scp=84896869970&partnerID=8YFLogxK

U2 - 10.1016/j.vascn.2014.01.004

DO - 10.1016/j.vascn.2014.01.004

M3 - Letter

C2 - 24468465

AN - SCOPUS:84896869970

VL - 69

SP - 205

EP - 207

JO - Journal of Pharmacological and Toxicological Methods

JF - Journal of Pharmacological and Toxicological Methods

SN - 1056-8719

IS - 2

ER -

ID: 9440488