Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Tandem repeats in the rodent genome and their mapping. / Ostromyshenskii, D. I.; Kuznetsova, I. S.; Komissarov, A. S.; Kartavtseva, I. V.; Podgornaya, O. I.
в: Cell and Tissue Biology, Том 9, № 3, 20.05.2015, стр. 217-225.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
}
TY - JOUR
T1 - Tandem repeats in the rodent genome and their mapping
AU - Ostromyshenskii, D. I.
AU - Kuznetsova, I. S.
AU - Komissarov, A. S.
AU - Kartavtseva, I. V.
AU - Podgornaya, O. I.
PY - 2015/5/20
Y1 - 2015/5/20
N2 - Tandemly repeated sequences are unique to eukaryotes and make up tens of percent of the higher eukaryote genome. However, the evolution of this class of sequences is poorly studied. In our paper, 62 families of Mus musculus tandem repeats are analyzed by bioinformatic methods, while 7 of them are analyzed by fluorescence in situ hybridization. It is shown that the same tandem repeat sets occur together only in closely related species of mice. However, even in such species, we observe differences in localization on chromosomes and the number of individual tandem repeats. With increasing evolutionary distance, only some of the tandem repeat families remain common for different species. It is shown that the use of a combination of bioinformatics and molecular biology techniques is very promising for further studies of tandem repeat evolution.
AB - Tandemly repeated sequences are unique to eukaryotes and make up tens of percent of the higher eukaryote genome. However, the evolution of this class of sequences is poorly studied. In our paper, 62 families of Mus musculus tandem repeats are analyzed by bioinformatic methods, while 7 of them are analyzed by fluorescence in situ hybridization. It is shown that the same tandem repeat sets occur together only in closely related species of mice. However, even in such species, we observe differences in localization on chromosomes and the number of individual tandem repeats. With increasing evolutionary distance, only some of the tandem repeat families remain common for different species. It is shown that the use of a combination of bioinformatics and molecular biology techniques is very promising for further studies of tandem repeat evolution.
KW - mouse
KW - Mus
KW - satellite DNA
KW - tandem repeats
UR - http://www.scopus.com/inward/record.url?scp=84935011275&partnerID=8YFLogxK
U2 - 10.1134/S1990519X15030116
DO - 10.1134/S1990519X15030116
M3 - Article
AN - SCOPUS:84935011275
VL - 9
SP - 217
EP - 225
JO - Cell and Tissue Biology
JF - Cell and Tissue Biology
SN - 1990-519X
IS - 3
ER -
ID: 41023937