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Synthesis of Novel 2-(4-Arylthiophenyl)quinazolin-4(3H)-ones Using S-Arylation Reaction. / Kudryashova, Ekaterina A.; Valieva, Maria I.; Shtaitz, Yaroslav K.; Moshkina, Tatyana N.; Slepukhin, Pavel A.; Gaviko, Vasily S.; Novikov, Alexander S.; Nosova, Emiliya V.; Kopchuk, Dmitry S.

в: Russian Journal of General Chemistry, Том 96, № 4, 45, 01.04.2026.

Результаты исследований: Научные публикации в периодических изданияхстатьяРецензирование

Harvard

Kudryashova, EA, Valieva, MI, Shtaitz, YK, Moshkina, TN, Slepukhin, PA, Gaviko, VS, Novikov, AS, Nosova, EV & Kopchuk, DS 2026, 'Synthesis of Novel 2-(4-Arylthiophenyl)quinazolin-4(3H)-ones Using S-Arylation Reaction', Russian Journal of General Chemistry, Том. 96, № 4, 45. https://doi.org/10.1134/s1070363225606763

APA

Kudryashova, E. A., Valieva, M. I., Shtaitz, Y. K., Moshkina, T. N., Slepukhin, P. A., Gaviko, V. S., Novikov, A. S., Nosova, E. V., & Kopchuk, D. S. (2026). Synthesis of Novel 2-(4-Arylthiophenyl)quinazolin-4(3H)-ones Using S-Arylation Reaction. Russian Journal of General Chemistry, 96(4), [45]. https://doi.org/10.1134/s1070363225606763

Vancouver

Kudryashova EA, Valieva MI, Shtaitz YK, Moshkina TN, Slepukhin PA, Gaviko VS и пр. Synthesis of Novel 2-(4-Arylthiophenyl)quinazolin-4(3H)-ones Using S-Arylation Reaction. Russian Journal of General Chemistry. 2026 Апр. 1;96(4). 45. https://doi.org/10.1134/s1070363225606763

Author

Kudryashova, Ekaterina A. ; Valieva, Maria I. ; Shtaitz, Yaroslav K. ; Moshkina, Tatyana N. ; Slepukhin, Pavel A. ; Gaviko, Vasily S. ; Novikov, Alexander S. ; Nosova, Emiliya V. ; Kopchuk, Dmitry S. / Synthesis of Novel 2-(4-Arylthiophenyl)quinazolin-4(3H)-ones Using S-Arylation Reaction. в: Russian Journal of General Chemistry. 2026 ; Том 96, № 4.

BibTeX

@article{2e75f1fbba7e4286830deec0b77fad5d,
title = "Synthesis of Novel 2-(4-Arylthiophenyl)quinazolin-4(3H)-ones Using S-Arylation Reaction",
abstract = "Abstract: 2-(4-Methylthiophenyl)quinazolin-4(3H)-one was prepared by condensation of 2-aminobenzamide with 4-methylthiobenzaldehyde in a two-step approach with isolation of the intermediate azomethine and subsequent dehydrogenation of the latter using DDQ. It was shown that the reaction of quinazolin-4(3H)-one with arynes, generated in situ from corresponding anthranilic acids, proceeds exclusively via an S-arylation pathway and leads to a series of previously unknown 2-substituted quinazolin-4(3H)-ones. A similar approach proved effective for the synthesis of 4-phenyl substituted 2-arylquinazolines, which expands the possibilities for modification of the quinazoline system. New quinazolines exhibit solid-state fluorescence with absolute quantum yield up to 10%, indicating their potential as functional luminescent materials.",
keywords = "S-arylation, anthranilic acids, diazotization, luminescence, quinazolin-4(3H)-one",
author = "Kudryashova, {Ekaterina A.} and Valieva, {Maria I.} and Shtaitz, {Yaroslav K.} and Moshkina, {Tatyana N.} and Slepukhin, {Pavel A.} and Gaviko, {Vasily S.} and Novikov, {Alexander S.} and Nosova, {Emiliya V.} and Kopchuk, {Dmitry S.}",
year = "2026",
month = apr,
day = "1",
doi = "10.1134/s1070363225606763",
language = "English",
volume = "96",
journal = "Russian Journal of General Chemistry",
issn = "1070-3632",
publisher = "МАИК {"}Наука/Интерпериодика{"}",
number = "4",

}

RIS

TY - JOUR

T1 - Synthesis of Novel 2-(4-Arylthiophenyl)quinazolin-4(3H)-ones Using S-Arylation Reaction

AU - Kudryashova, Ekaterina A.

AU - Valieva, Maria I.

AU - Shtaitz, Yaroslav K.

AU - Moshkina, Tatyana N.

AU - Slepukhin, Pavel A.

AU - Gaviko, Vasily S.

AU - Novikov, Alexander S.

AU - Nosova, Emiliya V.

AU - Kopchuk, Dmitry S.

PY - 2026/4/1

Y1 - 2026/4/1

N2 - Abstract: 2-(4-Methylthiophenyl)quinazolin-4(3H)-one was prepared by condensation of 2-aminobenzamide with 4-methylthiobenzaldehyde in a two-step approach with isolation of the intermediate azomethine and subsequent dehydrogenation of the latter using DDQ. It was shown that the reaction of quinazolin-4(3H)-one with arynes, generated in situ from corresponding anthranilic acids, proceeds exclusively via an S-arylation pathway and leads to a series of previously unknown 2-substituted quinazolin-4(3H)-ones. A similar approach proved effective for the synthesis of 4-phenyl substituted 2-arylquinazolines, which expands the possibilities for modification of the quinazoline system. New quinazolines exhibit solid-state fluorescence with absolute quantum yield up to 10%, indicating their potential as functional luminescent materials.

AB - Abstract: 2-(4-Methylthiophenyl)quinazolin-4(3H)-one was prepared by condensation of 2-aminobenzamide with 4-methylthiobenzaldehyde in a two-step approach with isolation of the intermediate azomethine and subsequent dehydrogenation of the latter using DDQ. It was shown that the reaction of quinazolin-4(3H)-one with arynes, generated in situ from corresponding anthranilic acids, proceeds exclusively via an S-arylation pathway and leads to a series of previously unknown 2-substituted quinazolin-4(3H)-ones. A similar approach proved effective for the synthesis of 4-phenyl substituted 2-arylquinazolines, which expands the possibilities for modification of the quinazoline system. New quinazolines exhibit solid-state fluorescence with absolute quantum yield up to 10%, indicating their potential as functional luminescent materials.

KW - S-arylation

KW - anthranilic acids

KW - diazotization

KW - luminescence

KW - quinazolin-4(3H)-one

UR - https://www.mendeley.com/catalogue/66e305ae-8206-364c-82d6-70fb92060178/

U2 - 10.1134/s1070363225606763

DO - 10.1134/s1070363225606763

M3 - Article

VL - 96

JO - Russian Journal of General Chemistry

JF - Russian Journal of General Chemistry

SN - 1070-3632

IS - 4

M1 - 45

ER -

ID: 149404648