TY - JOUR

T1 - Synthesis and Structural Characterization of Half-Sandwich Arene–Ruthenium(II) Complexes with Bis(imidazol-1-yl)methane, Imidazole and Benzimidazole

AU - Матвеевская, Владислава

AU - Павлов, Дмитрий

AU - Самсоненко, Денис

AU - Ермакова, Екатерина

AU - Клюшова, Любовь

AU - Байков, Сергей Валентинович

AU - Боярский, Вадим Павлович

AU - Потапов, Андрей

N1 - Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2021/5/4

Y1 - 2021/5/4

N2 - Mono-and binuclear arene–ruthenium(II) complexes with imidazole-containing ligands were prepared by the reaction of the ligands (L 1 = bis(imidazole-1-yl)methane; ImH = 1H-Imidazole; BImH = 1H-Benzimidazole) with [(p-cym)Ru(µ-Cl) 2 ] 2 dimers. When bis(imidazole-1-yl)methane re-acted with [(p-cym)Ru(µ-Cl) 2 ] 2 in methanol, a binuclear complex of the type [Ru 2 (L 1 ) 2 (p-cym) 2Cl 2 ]Cl 2 (2) with cyclic structure was synthesized, whereas by using acetonitrile as a solvent under the same reaction conditions, an unexpected C–N bond cleavage was observed, and a complex of formula [Ru(ImH) 2 (p-cym)Cl]Cl (1) with coordinated imidazole molecules was obtained. Another type of arene–ruthenium complex [Ru(BImH)(p-cym)Cl 2 ] (3) was obtained by the reaction of benzimidazole and [(p-cym)Ru(µ-Cl) 2 ] 2 . All compounds were characterized by spectral (FT-IR, NMR 1H, 13C) and single-crystal X-ray diffraction methods; their catalytic activity in transfer hydrogenation and the cytotoxicity against MCF-7 and HepG2 cells were evaluated.

AB - Mono-and binuclear arene–ruthenium(II) complexes with imidazole-containing ligands were prepared by the reaction of the ligands (L 1 = bis(imidazole-1-yl)methane; ImH = 1H-Imidazole; BImH = 1H-Benzimidazole) with [(p-cym)Ru(µ-Cl) 2 ] 2 dimers. When bis(imidazole-1-yl)methane re-acted with [(p-cym)Ru(µ-Cl) 2 ] 2 in methanol, a binuclear complex of the type [Ru 2 (L 1 ) 2 (p-cym) 2Cl 2 ]Cl 2 (2) with cyclic structure was synthesized, whereas by using acetonitrile as a solvent under the same reaction conditions, an unexpected C–N bond cleavage was observed, and a complex of formula [Ru(ImH) 2 (p-cym)Cl]Cl (1) with coordinated imidazole molecules was obtained. Another type of arene–ruthenium complex [Ru(BImH)(p-cym)Cl 2 ] (3) was obtained by the reaction of benzimidazole and [(p-cym)Ru(µ-Cl) 2 ] 2 . All compounds were characterized by spectral (FT-IR, NMR 1H, 13C) and single-crystal X-ray diffraction methods; their catalytic activity in transfer hydrogenation and the cytotoxicity against MCF-7 and HepG2 cells were evaluated.

KW - Arene–ruthenium complexes

KW - Benzimidazole

KW - Bis(imidazol-1-yl)methane

KW - Crystal structure

KW - Imidazole

UR - http://www.scopus.com/inward/record.url?scp=85106733729&partnerID=8YFLogxK

U2 - 10.3390/inorganics9050034

DO - 10.3390/inorganics9050034

M3 - Article

VL - 9

JO - Inorganics

JF - Inorganics

SN - 2304-6740

IS - 5

M1 - 34

ER -