Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
The reaction of 4-aryl-2-hydroxy-4-oxo-N-{4-[(1,3-thiazol-2-yl)sulfamoyl]phenyl}but-2-enamides with phenylhydrazine in glacial acetic acid afforded 5-aryl-N-{4-[(1,3-thiazol-2-yl)sulfamoyl]phenyl}-1-phenyl-1H-pyrazole-3-carboxamides. Treatment of the latter with an equimolar amount of silver nitrate in ethanol–DMF (2:1) gave the corresponding silver salts, while 5-aryl-N-{4-[(1,3-thiazol-2-yl)sulfamoyl]phenyl}-1-phenyl-1H-pyrazole-3-carboxamide sodium salts were obtained by reaction with sodium methoxide in methanol–DMF (1:1). The synthesized compounds were tested for analgesic, anti-inflammatory, and antimicrobial activities.
Язык оригинала | английский |
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Страницы (с-по) | 680-688 |
Число страниц | 9 |
Журнал | Russian Journal of General Chemistry |
Том | 89 |
Номер выпуска | 4 |
DOI | |
Состояние | Опубликовано - 1 апр 2019 |
ID: 45307342