Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Successful Pregnancy Outcome in Women with Recurrent IVF Failure and Anti-hCG Autoimmunity : A Report of Three Cases. / Muller, Valeria; Ob'edkova, Ksenia; Krikheli, Inna; Kogan, Igor; Fedorova, Irina; Lesik, Elena; Komarova, Evgenia; Gzgzyan, Alexandr.
в: Case Reports in Immunology, Том 2016, 4391537, 2016.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Successful Pregnancy Outcome in Women with Recurrent IVF Failure and Anti-hCG Autoimmunity
T2 - A Report of Three Cases
AU - Muller, Valeria
AU - Ob'edkova, Ksenia
AU - Krikheli, Inna
AU - Kogan, Igor
AU - Fedorova, Irina
AU - Lesik, Elena
AU - Komarova, Evgenia
AU - Gzgzyan, Alexandr
N1 - Publisher Copyright: © 2016 Valeria Muller et al. Copyright: Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2016
Y1 - 2016
N2 - We report three cases of effective management of infertility in women with a history of repeated unsuccessful IVF attempts, who have developed antibodies to hCG. A novel approach to conservative treatment of immunologic reproductive failure, suggested for selected patients, included membrane plasmapheresis, combined prednisolone, and intravenous immunoglobulin therapy. No adverse side effects were observed; all cases resulted in pregnancy and subsequent life births. In order to be given an adequate efficient treatment, women with recurrent implantation failure should be suspected for autoimmune factor of infertility and its possible association with anti-hCG autoimmunity.
AB - We report three cases of effective management of infertility in women with a history of repeated unsuccessful IVF attempts, who have developed antibodies to hCG. A novel approach to conservative treatment of immunologic reproductive failure, suggested for selected patients, included membrane plasmapheresis, combined prednisolone, and intravenous immunoglobulin therapy. No adverse side effects were observed; all cases resulted in pregnancy and subsequent life births. In order to be given an adequate efficient treatment, women with recurrent implantation failure should be suspected for autoimmune factor of infertility and its possible association with anti-hCG autoimmunity.
UR - http://www.scopus.com/inward/record.url?scp=85043609493&partnerID=8YFLogxK
U2 - 10.1155/2016/4391537
DO - 10.1155/2016/4391537
M3 - Article
AN - SCOPUS:85043609493
VL - 2016
JO - Case Reports in Immunology
JF - Case Reports in Immunology
SN - 2090-6609
M1 - 4391537
ER -
ID: 76495658