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Structural Study of the Complex Formed by Ceruloplasmin and Macrophage Migration Inhibitory Factor. / Sokolov, A. V.; Dadinova, L. A.; Petoukhov, M. V.; Bourenkov, G.; Dubova, K. M.; Amarantov, S. V.; Volkov, V. V.; Kostevich, V. A.; Gorbunov, N. P.; Grudinina, N. A.; Vasilyev, V. B.; Samygina, V. R.

в: Biochemistry (Moscow), Том 83, № 6, 01.06.2018, стр. 701-707.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Sokolov, AV, Dadinova, LA, Petoukhov, MV, Bourenkov, G, Dubova, KM, Amarantov, SV, Volkov, VV, Kostevich, VA, Gorbunov, NP, Grudinina, NA, Vasilyev, VB & Samygina, VR 2018, 'Structural Study of the Complex Formed by Ceruloplasmin and Macrophage Migration Inhibitory Factor', Biochemistry (Moscow), Том. 83, № 6, стр. 701-707. https://doi.org/10.1134/S000629791806007X

APA

Sokolov, A. V., Dadinova, L. A., Petoukhov, M. V., Bourenkov, G., Dubova, K. M., Amarantov, S. V., Volkov, V. V., Kostevich, V. A., Gorbunov, N. P., Grudinina, N. A., Vasilyev, V. B., & Samygina, V. R. (2018). Structural Study of the Complex Formed by Ceruloplasmin and Macrophage Migration Inhibitory Factor. Biochemistry (Moscow), 83(6), 701-707. https://doi.org/10.1134/S000629791806007X

Vancouver

Sokolov AV, Dadinova LA, Petoukhov MV, Bourenkov G, Dubova KM, Amarantov SV и пр. Structural Study of the Complex Formed by Ceruloplasmin and Macrophage Migration Inhibitory Factor. Biochemistry (Moscow). 2018 Июнь 1;83(6):701-707. https://doi.org/10.1134/S000629791806007X

Author

Sokolov, A. V. ; Dadinova, L. A. ; Petoukhov, M. V. ; Bourenkov, G. ; Dubova, K. M. ; Amarantov, S. V. ; Volkov, V. V. ; Kostevich, V. A. ; Gorbunov, N. P. ; Grudinina, N. A. ; Vasilyev, V. B. ; Samygina, V. R. / Structural Study of the Complex Formed by Ceruloplasmin and Macrophage Migration Inhibitory Factor. в: Biochemistry (Moscow). 2018 ; Том 83, № 6. стр. 701-707.

BibTeX

@article{a864623c3172499195444fde772697fb,
title = "Structural Study of the Complex Formed by Ceruloplasmin and Macrophage Migration Inhibitory Factor",
abstract = "Macrophage migration inhibitory factor (MIF) is a key proinflammatory cytokine. Inhibitors of tautomerase activity of MIF are perspective antiinflammatory compounds. Ceruloplasmin, the copper-containing ferroxidase of blood plasma, is a noncompetitive inhibitor of tautomerase activity of MIF in the reaction with p-hydroxyphenylpyruvate. Small-angle X-ray scattering established a model of the complex formed by MIF and ceruloplasmin. Crystallographic analysis of MIF with a modified active site supports the model. The stoichiometry of 3 CP/MIF trimer complex was established using gel filtration. Conformity of novel data concerning the interaction regions in the studied proteins with previous biochemical data is discussed.",
keywords = "ceruloplasmin, macrophage migration inhibitory factor, protein–protein interactions, small-angle X-ray scattering, X-ray analysis",
author = "Sokolov, {A. V.} and Dadinova, {L. A.} and Petoukhov, {M. V.} and G. Bourenkov and Dubova, {K. M.} and Amarantov, {S. V.} and Volkov, {V. V.} and Kostevich, {V. A.} and Gorbunov, {N. P.} and Grudinina, {N. A.} and Vasilyev, {V. B.} and Samygina, {V. R.}",
year = "2018",
month = jun,
day = "1",
doi = "10.1134/S000629791806007X",
language = "English",
volume = "83",
pages = "701--707",
journal = "Biochemistry (Moscow)",
issn = "0006-2979",
publisher = "МАИК {"}Наука/Интерпериодика{"}",
number = "6",

}

RIS

TY - JOUR

T1 - Structural Study of the Complex Formed by Ceruloplasmin and Macrophage Migration Inhibitory Factor

AU - Sokolov, A. V.

AU - Dadinova, L. A.

AU - Petoukhov, M. V.

AU - Bourenkov, G.

AU - Dubova, K. M.

AU - Amarantov, S. V.

AU - Volkov, V. V.

AU - Kostevich, V. A.

AU - Gorbunov, N. P.

AU - Grudinina, N. A.

AU - Vasilyev, V. B.

AU - Samygina, V. R.

PY - 2018/6/1

Y1 - 2018/6/1

N2 - Macrophage migration inhibitory factor (MIF) is a key proinflammatory cytokine. Inhibitors of tautomerase activity of MIF are perspective antiinflammatory compounds. Ceruloplasmin, the copper-containing ferroxidase of blood plasma, is a noncompetitive inhibitor of tautomerase activity of MIF in the reaction with p-hydroxyphenylpyruvate. Small-angle X-ray scattering established a model of the complex formed by MIF and ceruloplasmin. Crystallographic analysis of MIF with a modified active site supports the model. The stoichiometry of 3 CP/MIF trimer complex was established using gel filtration. Conformity of novel data concerning the interaction regions in the studied proteins with previous biochemical data is discussed.

AB - Macrophage migration inhibitory factor (MIF) is a key proinflammatory cytokine. Inhibitors of tautomerase activity of MIF are perspective antiinflammatory compounds. Ceruloplasmin, the copper-containing ferroxidase of blood plasma, is a noncompetitive inhibitor of tautomerase activity of MIF in the reaction with p-hydroxyphenylpyruvate. Small-angle X-ray scattering established a model of the complex formed by MIF and ceruloplasmin. Crystallographic analysis of MIF with a modified active site supports the model. The stoichiometry of 3 CP/MIF trimer complex was established using gel filtration. Conformity of novel data concerning the interaction regions in the studied proteins with previous biochemical data is discussed.

KW - ceruloplasmin

KW - macrophage migration inhibitory factor

KW - protein–protein interactions

KW - small-angle X-ray scattering

KW - X-ray analysis

UR - http://www.scopus.com/inward/record.url?scp=85048310374&partnerID=8YFLogxK

U2 - 10.1134/S000629791806007X

DO - 10.1134/S000629791806007X

M3 - Article

C2 - 30195326

AN - SCOPUS:85048310374

VL - 83

SP - 701

EP - 707

JO - Biochemistry (Moscow)

JF - Biochemistry (Moscow)

SN - 0006-2979

IS - 6

ER -

ID: 42247011