Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Steroidogenesis in patients with various adrenal cortex diseases as studied by reversed-phase high-performance liquid chromatography. / Kartsova, A. A.; Velikanova, L. I.; Pavlova, E. G.; Bessonova, E. A.
в: Journal of Analytical Chemistry, Том 59, № 10, 01.10.2004, стр. 976-982.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
}
TY - JOUR
T1 - Steroidogenesis in patients with various adrenal cortex diseases as studied by reversed-phase high-performance liquid chromatography
AU - Kartsova, A. A.
AU - Velikanova, L. I.
AU - Pavlova, E. G.
AU - Bessonova, E. A.
PY - 2004/10/1
Y1 - 2004/10/1
N2 - A method is proposed for the quantitative determination of diagnostically important corticosteroids (cortisol, cortisone, corticosterone, 11-deoxycorticosterone, and 11-deoxycortisol) in blood serum and urine (cortisol and cortisone) in an isocratic mode of reversed-phase high-performance liquid chromatography (RP HPLC) with the use of β-cyclodextrin as a component of the mobile phase (CH 3CN : H 2O). Biological fluids (blood serum and urine) from a group of healthy donors and patients with various endocrine diseases (Cushing's syndrome, congenital adrenal hyperplasia, aldosteroma, and adrenal cortex carcinoma) were examined, and characteristic chromatographic steroid profiles were obtained for these disturbances.
AB - A method is proposed for the quantitative determination of diagnostically important corticosteroids (cortisol, cortisone, corticosterone, 11-deoxycorticosterone, and 11-deoxycortisol) in blood serum and urine (cortisol and cortisone) in an isocratic mode of reversed-phase high-performance liquid chromatography (RP HPLC) with the use of β-cyclodextrin as a component of the mobile phase (CH 3CN : H 2O). Biological fluids (blood serum and urine) from a group of healthy donors and patients with various endocrine diseases (Cushing's syndrome, congenital adrenal hyperplasia, aldosteroma, and adrenal cortex carcinoma) were examined, and characteristic chromatographic steroid profiles were obtained for these disturbances.
UR - http://www.scopus.com/inward/record.url?scp=5444244187&partnerID=8YFLogxK
U2 - 10.1023/B:JANC.0000043915.76485.e0
DO - 10.1023/B:JANC.0000043915.76485.e0
M3 - Article
AN - SCOPUS:5444244187
VL - 59
SP - 976
EP - 982
JO - Journal of Analytical Chemistry
JF - Journal of Analytical Chemistry
SN - 1061-9348
IS - 10
ER -
ID: 61637400