Stabilization of DNA by sodium and magnesium ions during the synthesis of DNA-bridged gold nanoparticles

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Stabilization of DNA by sodium and magnesium ions during the synthesis of DNA-bridged gold nanoparticles. / Sokolov, Petr A.; Ramazanov, Ruslan R.; Rolich, Valeriy I.; Popova, Maria A.; Shalygin, Vyacheslav E.; Kasyanenko, Nina A.

в: Nanotechnology, Том 32, № 4, 045604, 22.01.2021.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

BibTeX

@article{5011b9507f9741c784b779f227e30238,

title = "Stabilization of DNA by sodium and magnesium ions during the synthesis of DNA-bridged gold nanoparticles",

abstract = "Nanostructures synthesized using DNA-conjugated gold nanoparticles have a wide range of applications in the field of biosensorics. The stability of the DNA duplex plays a critical role as it determines the final geometry of these nanostructures. The main way to control DNA stability is to maintain a high ionic strength of the buffer solution; at the same time, high salt concentrations lead to an aggregation of nanoparticles. In this study, by means of the instrumentality of DNA-bridged seeds using tris(hydroxymethyl)aminomethane as a soft reducing agent the dumbbell-like gold nanoparticles up to 35 nm were synthesized with a high concentration of sodium ions of up to 100 mM and magnesium ions up to 1 mM. We also examined at the atomic level the details of the effect of the gold nanoparticle surface, as well as Na+ and Mg2+ ions, on the stability of nucleotide pairs located in close proximity to the grafting site.",

keywords = "DNA, Dumbbells, Gold, Nanoparticles, Plasmonics, Salt, salt, UNIFORM, SIZES, ADSORPTION, CYTOSINE, gold, DENSITY, dumbbells, nanoparticles, plasmonics, GROWTH, SURFACE, NUCLEOBASES",

author = "Sokolov, {Petr A.} and Ramazanov, {Ruslan R.} and Rolich, {Valeriy I.} and Popova, {Maria A.} and Shalygin, {Vyacheslav E.} and Kasyanenko, {Nina A.}",

year = "2021",

month = jan,

day = "22",

doi = "10.1088/1361-6528/abc037",

language = "English",

volume = "32",

journal = "Nanotechnology",

issn = "0957-4484",

publisher = "IOP Publishing Ltd.",

number = "4",

}

RIS

TY - JOUR

T1 - Stabilization of DNA by sodium and magnesium ions during the synthesis of DNA-bridged gold nanoparticles

AU - Sokolov, Petr A.

AU - Ramazanov, Ruslan R.

AU - Rolich, Valeriy I.

AU - Popova, Maria A.

AU - Shalygin, Vyacheslav E.

AU - Kasyanenko, Nina A.

PY - 2021/1/22

Y1 - 2021/1/22

N2 - Nanostructures synthesized using DNA-conjugated gold nanoparticles have a wide range of applications in the field of biosensorics. The stability of the DNA duplex plays a critical role as it determines the final geometry of these nanostructures. The main way to control DNA stability is to maintain a high ionic strength of the buffer solution; at the same time, high salt concentrations lead to an aggregation of nanoparticles. In this study, by means of the instrumentality of DNA-bridged seeds using tris(hydroxymethyl)aminomethane as a soft reducing agent the dumbbell-like gold nanoparticles up to 35 nm were synthesized with a high concentration of sodium ions of up to 100 mM and magnesium ions up to 1 mM. We also examined at the atomic level the details of the effect of the gold nanoparticle surface, as well as Na+ and Mg2+ ions, on the stability of nucleotide pairs located in close proximity to the grafting site.

AB - Nanostructures synthesized using DNA-conjugated gold nanoparticles have a wide range of applications in the field of biosensorics. The stability of the DNA duplex plays a critical role as it determines the final geometry of these nanostructures. The main way to control DNA stability is to maintain a high ionic strength of the buffer solution; at the same time, high salt concentrations lead to an aggregation of nanoparticles. In this study, by means of the instrumentality of DNA-bridged seeds using tris(hydroxymethyl)aminomethane as a soft reducing agent the dumbbell-like gold nanoparticles up to 35 nm were synthesized with a high concentration of sodium ions of up to 100 mM and magnesium ions up to 1 mM. We also examined at the atomic level the details of the effect of the gold nanoparticle surface, as well as Na+ and Mg2+ ions, on the stability of nucleotide pairs located in close proximity to the grafting site.

KW - DNA

KW - Dumbbells

KW - Gold

KW - Nanoparticles

KW - Plasmonics

KW - Salt

KW - salt

KW - UNIFORM

KW - SIZES

KW - ADSORPTION

KW - CYTOSINE

KW - gold

KW - DENSITY

KW - dumbbells

KW - nanoparticles

KW - plasmonics

KW - GROWTH

KW - SURFACE

KW - NUCLEOBASES

UR - http://www.scopus.com/inward/record.url?scp=85095861186&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/8dc84096-8b0a-3d21-8f14-00d317a81864/

U2 - 10.1088/1361-6528/abc037

DO - 10.1088/1361-6528/abc037

M3 - Article

C2 - 33045696

AN - SCOPUS:85095861186

VL - 32

JO - Nanotechnology

JF - Nanotechnology

SN - 0957-4484

IS - 4

M1 - 045604

ER -

ID: 72060545