Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
SIGMA-1 RECEPTOR AGONIST AMITRIPTYLINE INHIBITS STORE-DEPENDENT Ca2+ ENTRY IN MACROPHAGES. / Krutetskaya, Z. I. ; Milenina, L. S. ; Antonov, V. G. ; Nozdrachev, A. D. .
в: Doklady Biochemistry and Biophysics, Том 488, № 1, 2019, стр. 307-310.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - SIGMA-1 RECEPTOR AGONIST AMITRIPTYLINE INHIBITS STORE-DEPENDENT Ca2+ ENTRY IN MACROPHAGES
AU - Krutetskaya, Z. I.
AU - Milenina, L. S.
AU - Antonov, V. G.
AU - Nozdrachev, A. D.
N1 - Krutetskaya, Z.I., Milenina, L.S., Antonov, V.G. et al. Sigma-1 Receptor Agonist Amitriptyline Inhibits Store-Dependent Ca2+ Entry in Macrophages. Dokl Biochem Biophys 488, 307–310 (2019). https://doi.org/10.1134/S1607672919050041
PY - 2019
Y1 - 2019
N2 - Abstract: Using Fura-2AM microfluorimetry, we have shown for the first time that sigma-1 receptor agonist–tricyclic antidepressant amitriptyline—significantly inhibits store-dependent Ca 2+ entry, induced by endoplasmic Ca 2+-ATPase inhibitors thapsigargin and cyclopiazonic acid, in rat peritoneal macrophages. The results suggest a possible involvement of sigma-1 receptors in the regulation of store-dependent Ca 2+ entry in macrophages.
AB - Abstract: Using Fura-2AM microfluorimetry, we have shown for the first time that sigma-1 receptor agonist–tricyclic antidepressant amitriptyline—significantly inhibits store-dependent Ca 2+ entry, induced by endoplasmic Ca 2+-ATPase inhibitors thapsigargin and cyclopiazonic acid, in rat peritoneal macrophages. The results suggest a possible involvement of sigma-1 receptors in the regulation of store-dependent Ca 2+ entry in macrophages.
UR - http://www.scopus.com/inward/record.url?scp=85075536490&partnerID=8YFLogxK
UR - https://elibrary.ru/item.asp?id=43205056
U2 - DOI: 10.1134/S1607672919050041
DO - DOI: 10.1134/S1607672919050041
M3 - Article
VL - 488
SP - 307
EP - 310
JO - Doklady Biochemistry and Biophysics
JF - Doklady Biochemistry and Biophysics
SN - 1607-6729
IS - 1
ER -
ID: 49296627