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Short-term restraint and emotional-painful stressors increase DNA instability in different brain areas of rats with contrast excitability. / Щербинина, Вероника Дмитриевна; Даев, Евгений Владиславович; Павлова, Марина Борисовна; Дюжикова, Наталья Алековна.

в: Neuroscience and Behavioral Physiology, Том 54, 02.10.2024.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Щербинина, ВД, Даев, ЕВ, Павлова, МБ & Дюжикова, НА 2024, 'Short-term restraint and emotional-painful stressors increase DNA instability in different brain areas of rats with contrast excitability', Neuroscience and Behavioral Physiology, Том. 54. https://doi.org/10.1007/s11055-024-01692-w

APA

Щербинина, В. Д., Даев, Е. В., Павлова, М. Б., & Дюжикова, Н. А. (2024). Short-term restraint and emotional-painful stressors increase DNA instability in different brain areas of rats with contrast excitability. Neuroscience and Behavioral Physiology, 54. https://doi.org/10.1007/s11055-024-01692-w

Vancouver

Щербинина ВД, Даев ЕВ, Павлова МБ, Дюжикова НА. Short-term restraint and emotional-painful stressors increase DNA instability in different brain areas of rats with contrast excitability. Neuroscience and Behavioral Physiology. 2024 Окт. 2;54. https://doi.org/10.1007/s11055-024-01692-w

Author

Щербинина, Вероника Дмитриевна ; Даев, Евгений Владиславович ; Павлова, Марина Борисовна ; Дюжикова, Наталья Алековна. / Short-term restraint and emotional-painful stressors increase DNA instability in different brain areas of rats with contrast excitability. в: Neuroscience and Behavioral Physiology. 2024 ; Том 54.

BibTeX

@article{431e876cdaaf4f3590d694e34ab0d1bf,
title = "Short-term restraint and emotional-painful stressors increase DNA instability in different brain areas of rats with contrast excitability",
abstract = "Stress-reaction developed after exposure to stressors of different natures, increases the level of DNA damage in cells of target organs, including the central nervous system. However, the time of stressing exposure needed to induce genome destabilization in different brain areas and individual differences in animals defining their brain cell genome response to stressors is unclear. In this research, we show that acute stressors (2-h immobilization or 13-min emotional-painful stressor) increase the level of DNA damage in at least one of the brain regions studied: the prefrontal cortex, hippocampus, and amygdala in rat strains with the high or low threshold of nerve tibialis excitability, and non-selected Wistar rats. The results reveal the interstrain differences in the genome response to acute stressors of each brain area, different from the repeated emotional-painful stressor effects shown earlier.",
keywords = "Stress; Nervous system excitability; DNA damage; Prefrontal cortex; Hippocampus; Amygdala, Amygdala, DNA damage, Prefrontal cortex, Hippocampus, Stress, Nervous system excitability",
author = "Щербинина, {Вероника Дмитриевна} and Даев, {Евгений Владиславович} and Павлова, {Марина Борисовна} and Дюжикова, {Наталья Алековна}",
year = "2024",
month = oct,
day = "2",
doi = "10.1007/s11055-024-01692-w",
language = "English",
volume = "54",
journal = "Neuroscience and Behavioral Physiology",
issn = "0097-0549",
publisher = "Springer Nature",

}

RIS

TY - JOUR

T1 - Short-term restraint and emotional-painful stressors increase DNA instability in different brain areas of rats with contrast excitability

AU - Щербинина, Вероника Дмитриевна

AU - Даев, Евгений Владиславович

AU - Павлова, Марина Борисовна

AU - Дюжикова, Наталья Алековна

PY - 2024/10/2

Y1 - 2024/10/2

N2 - Stress-reaction developed after exposure to stressors of different natures, increases the level of DNA damage in cells of target organs, including the central nervous system. However, the time of stressing exposure needed to induce genome destabilization in different brain areas and individual differences in animals defining their brain cell genome response to stressors is unclear. In this research, we show that acute stressors (2-h immobilization or 13-min emotional-painful stressor) increase the level of DNA damage in at least one of the brain regions studied: the prefrontal cortex, hippocampus, and amygdala in rat strains with the high or low threshold of nerve tibialis excitability, and non-selected Wistar rats. The results reveal the interstrain differences in the genome response to acute stressors of each brain area, different from the repeated emotional-painful stressor effects shown earlier.

AB - Stress-reaction developed after exposure to stressors of different natures, increases the level of DNA damage in cells of target organs, including the central nervous system. However, the time of stressing exposure needed to induce genome destabilization in different brain areas and individual differences in animals defining their brain cell genome response to stressors is unclear. In this research, we show that acute stressors (2-h immobilization or 13-min emotional-painful stressor) increase the level of DNA damage in at least one of the brain regions studied: the prefrontal cortex, hippocampus, and amygdala in rat strains with the high or low threshold of nerve tibialis excitability, and non-selected Wistar rats. The results reveal the interstrain differences in the genome response to acute stressors of each brain area, different from the repeated emotional-painful stressor effects shown earlier.

KW - Stress; Nervous system excitability; DNA damage; Prefrontal cortex; Hippocampus; Amygdala

KW - Amygdala

KW - DNA damage

KW - Prefrontal cortex

KW - Hippocampus

KW - Stress

KW - Nervous system excitability

UR - https://www.mendeley.com/catalogue/836cc248-7441-3226-a015-6b50d64cbdb6/

U2 - 10.1007/s11055-024-01692-w

DO - 10.1007/s11055-024-01692-w

M3 - Article

VL - 54

JO - Neuroscience and Behavioral Physiology

JF - Neuroscience and Behavioral Physiology

SN - 0097-0549

ER -

ID: 124623578