Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
SGTK: a toolkit for visualization and assessment of scaffold graphs. / Kunyavskaya, O.; Prjibelski, A.D.
в: Bioinformatics, Том 35, № 13, 01.07.2019, стр. 2303-2305.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
}
TY - JOUR
T1 - SGTK: a toolkit for visualization and assessment of scaffold graphs
AU - Kunyavskaya, O.
AU - Prjibelski, A.D.
N1 - Publisher Copyright: © The Author 2018. Published by Oxford University Press. All rights reserved.
PY - 2019/7/1
Y1 - 2019/7/1
N2 - Scaffolding is an important step in every genome assembly pipeline, which allows to order contigs into longer sequences using various types of linkage information, such as mate-pair libraries and long reads. In this work, we operate with a notion of a scaffold graph-a graph, verti-ces of which correspond to the assembled contigs and edges represent connections between them. We present a software package called Scaffold Graph ToolKit that allows to construct and visualize scaffold graphs using different kinds of sequencing data. We show that the scaffold graph appears to be useful for analyzing and assessing genome assemblies, and demonstrate several use cases that can be helpful for both assembly software developers and their users.
AB - Scaffolding is an important step in every genome assembly pipeline, which allows to order contigs into longer sequences using various types of linkage information, such as mate-pair libraries and long reads. In this work, we operate with a notion of a scaffold graph-a graph, verti-ces of which correspond to the assembled contigs and edges represent connections between them. We present a software package called Scaffold Graph ToolKit that allows to construct and visualize scaffold graphs using different kinds of sequencing data. We show that the scaffold graph appears to be useful for analyzing and assessing genome assemblies, and demonstrate several use cases that can be helpful for both assembly software developers and their users.
KW - GENOME
KW - ABYSS
UR - http://www.scopus.com/inward/record.url?scp=85069784514&partnerID=8YFLogxK
UR - http://www.mendeley.com/research/sgtk-toolkit-visualization-assessment-scaffold-graphs
U2 - 10.1093/bioinformatics/bty956
DO - 10.1093/bioinformatics/bty956
M3 - Article
C2 - 30475983
VL - 35
SP - 2303
EP - 2305
JO - Bioinformatics
JF - Bioinformatics
SN - 1367-4803
IS - 13
ER -
ID: 36061186