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Receptor-ligand interactions : Advanced biomedical applications. / Guryanov, Ivan; Fiorucci, Stefano; Tennikova, Tatiana.

в: Materials Science and Engineering C, Том 68, 01.11.2016, стр. 890-903.

Результаты исследований: Научные публикации в периодических изданияхОбзорная статьяРецензирование

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Guryanov, Ivan ; Fiorucci, Stefano ; Tennikova, Tatiana. / Receptor-ligand interactions : Advanced biomedical applications. в: Materials Science and Engineering C. 2016 ; Том 68. стр. 890-903.

BibTeX

@article{39b48a9fe7f34fa69c739d31c8e1255f,
title = "Receptor-ligand interactions: Advanced biomedical applications",
abstract = "Receptor-ligand interactions (RLIs) are at the base of all biological events occurring in living cells. The understanding of interactions between complementary macromolecules in biological systems represents a high-priority research area in bionanotechnology to design the artificial systems mimicking natural processes. This review summarizes and analyzes RLIs in some cutting-edge biomedical fields, in particular, for the preparation of novel stationary phases to separate complex biological mixtures in medical diagnostics, for the design of ultrasensitive biosensors for identification of biomarkers of various diseases at early stages, as well as in the development of innovative biomaterials and approaches for regenerative medicine. All these biotechnological fields are closely related, because their success depends on a proper choice, combination and spatial disposition of the single components of ligand-receptor pairs on the surface of appropriately designed support.",
keywords = "Affinity chromatography, Biosensor, Ligand, Receptor, Regenerative medicine, Tissue engineering",
author = "Ivan Guryanov and Stefano Fiorucci and Tatiana Tennikova",
note = "Publisher Copyright: {\textcopyright} 2016 Elsevier B.V.",
year = "2016",
month = nov,
day = "1",
doi = "10.1016/j.msec.2016.07.072",
language = "English",
volume = "68",
pages = "890--903",
journal = "Materials Science and Engineering C",
issn = "0928-4931",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Receptor-ligand interactions

T2 - Advanced biomedical applications

AU - Guryanov, Ivan

AU - Fiorucci, Stefano

AU - Tennikova, Tatiana

N1 - Publisher Copyright: © 2016 Elsevier B.V.

PY - 2016/11/1

Y1 - 2016/11/1

N2 - Receptor-ligand interactions (RLIs) are at the base of all biological events occurring in living cells. The understanding of interactions between complementary macromolecules in biological systems represents a high-priority research area in bionanotechnology to design the artificial systems mimicking natural processes. This review summarizes and analyzes RLIs in some cutting-edge biomedical fields, in particular, for the preparation of novel stationary phases to separate complex biological mixtures in medical diagnostics, for the design of ultrasensitive biosensors for identification of biomarkers of various diseases at early stages, as well as in the development of innovative biomaterials and approaches for regenerative medicine. All these biotechnological fields are closely related, because their success depends on a proper choice, combination and spatial disposition of the single components of ligand-receptor pairs on the surface of appropriately designed support.

AB - Receptor-ligand interactions (RLIs) are at the base of all biological events occurring in living cells. The understanding of interactions between complementary macromolecules in biological systems represents a high-priority research area in bionanotechnology to design the artificial systems mimicking natural processes. This review summarizes and analyzes RLIs in some cutting-edge biomedical fields, in particular, for the preparation of novel stationary phases to separate complex biological mixtures in medical diagnostics, for the design of ultrasensitive biosensors for identification of biomarkers of various diseases at early stages, as well as in the development of innovative biomaterials and approaches for regenerative medicine. All these biotechnological fields are closely related, because their success depends on a proper choice, combination and spatial disposition of the single components of ligand-receptor pairs on the surface of appropriately designed support.

KW - Affinity chromatography

KW - Biosensor

KW - Ligand

KW - Receptor

KW - Regenerative medicine

KW - Tissue engineering

UR - http://www.scopus.com/inward/record.url?scp=84989924508&partnerID=8YFLogxK

U2 - 10.1016/j.msec.2016.07.072

DO - 10.1016/j.msec.2016.07.072

M3 - Review article

C2 - 27524092

VL - 68

SP - 890

EP - 903

JO - Materials Science and Engineering C

JF - Materials Science and Engineering C

SN - 0928-4931

ER -

ID: 7952232