Результаты исследований: Научные публикации в периодических изданиях › Обзорная статья › Рецензирование
Recent advances in isoxazole chemistry. / Galenko, A.V.; Khlebnikov, A.F.; Novikov, M.S.; Pakalnis, V.V.; Rostovskii, N.V.
в: Russian Chemical Reviews, Том 84, № 4, 01.04.2015, стр. 335-377.Результаты исследований: Научные публикации в периодических изданиях › Обзорная статья › Рецензирование
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TY - JOUR
T1 - Recent advances in isoxazole chemistry
AU - Galenko, A.V.
AU - Khlebnikov, A.F.
AU - Novikov, M.S.
AU - Pakalnis, V.V.
AU - Rostovskii, N.V.
PY - 2015/4/1
Y1 - 2015/4/1
N2 - The preparation methods and reactions of isoxazoles are described and systematized on the basis of analysis of the literaturepublished from 2005 to present. In the discussion of synthesis, major attention is focused on the most efficient approaches:condensation of hydroxylamine with 1,3-dielectrophiles and reactions of nitrile oxides with alkenes and alkynes. Five-membered ring opening reactions leading to acyclic functionalized or other heterocyclic compounds are considered. Thetransformations of isoxazole derivatives that occur without ring cleavage to form fused heterocyclic systems, as well asreactions that lead to the introduction of C-substituents into isoxazoles, are considered. Data on the biological activity ofsome isoxazole derivatives are reported.The bibliography includes 439 references.
AB - The preparation methods and reactions of isoxazoles are described and systematized on the basis of analysis of the literaturepublished from 2005 to present. In the discussion of synthesis, major attention is focused on the most efficient approaches:condensation of hydroxylamine with 1,3-dielectrophiles and reactions of nitrile oxides with alkenes and alkynes. Five-membered ring opening reactions leading to acyclic functionalized or other heterocyclic compounds are considered. Thetransformations of isoxazole derivatives that occur without ring cleavage to form fused heterocyclic systems, as well asreactions that lead to the introduction of C-substituents into isoxazoles, are considered. Data on the biological activity ofsome isoxazole derivatives are reported.The bibliography includes 439 references.
UR - http://iopscience.iop.org/article/10.1070/RCR4503/meta
U2 - 10.1070/RCR4503
DO - 10.1070/RCR4503
M3 - Review article
VL - 84
SP - 335
EP - 377
JO - Russian Chemical Reviews
JF - Russian Chemical Reviews
SN - 0036-021X
IS - 4
ER -
ID: 3923944