Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Reaction of dichlorocarbene with 3,3-dialkyl-3,4-dihydroisoquinolines results in the formation of gemdichloroazirino[2,1-a ]isoquinolines, which are in turn converted to 3-benzazepinones upon hydrolysis. Reaction of dichlorocarbene with the ethyl ester or amide of (3,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-1-ylidene)acetic acid is accompanied by rearrangement of the intermediate carbene adducts at the enamine C=C bond and results in the formation of a 1-azadiene, 3-(3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-3-chloroacrylic acid ethyl ester, and a spirolactam, 3,3-dimethyl-3-chlorospiro[1,2,3,4-tetrahydroisoquinoline-1,2′-pyrrole]-5′(2′H)-one, respectively.
Язык оригинала | английский |
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Страницы (с-по) | 909-913 |
Число страниц | 5 |
Журнал | Chemistry of Heterocyclic Compounds |
Том | 26 |
Номер выпуска | 8 |
DOI | |
Состояние | Опубликовано - 1 авг 1990 |
ID: 28245997