New data on the stratigraphy, faults, and formation history of lower to middle Pleistocene rocks in Late Cenozoic basins of northwestern Armenia are presented. It has been established that the low-mountain topography created by tectonic movements and volcanic activity existed in the region by the onset of the Pleistocene. The manifestations of two geodynamic structure-forming factors became clear in Pleistocene: (i) collisional interaction of plates due to near-meridional compression and (ii) deep tectogenesis and magma formation expressed in the distribution of vertical movements and volcanism. The general uplift of the territory, which was also related to deep processes, reached 350–500 m in basins and 600–800 m in mountain ranges over the last 0.5 Ma. The early Pleistocene (~1.8 Ma) low- and medium-mountain topography has been reconstructed by subtraction of the latest deformations and uplift of the territory. Ancient human ancestry appeared at that time.