TY - JOUR

T1 - Professional athletic performance efficiency versus metabolism controlling gene polymorphism and pharmacological support

AU - Buznik, G.V.

AU - Pyatibra, A.O.

AU - Rodichkin, P.V.

AU - Shabanov, P.D.

PY - 2018/4/2

Y1 - 2018/4/2

N2 - The study was designed to analyze the bodily homeostasis in extreme situations versus the metabolism controlling gene polymorphism. The study data showed correlations of different gene alleles with adaptability to high physical loads. Subject to a pharmacological analysis under the study were the effects of Metaprot and Citoflavin on the athletes' functionality rates under extreme physical loads. Metaprot was found to improve the adaptation mechanisms under extreme loads both in the biochemical and organs-specific levels, with significant savings in the performance rehabilitation time. Citoflavin was also tested to be of positive effect on the bodily adaptation mechanisms, particularly in rehabilitation periods; with the rehabilitative effects of Citoflavin found the most expressed in the athletes tested with different combinations of homozygote alleles associated with the lower aerobic productivity rates. The study data and analyses give grounds to conclude that the actual effects of pharmacological agents of nootropic action are largely determined by the anaerobic metabolism controlling gene polymorphism.

AB - The study was designed to analyze the bodily homeostasis in extreme situations versus the metabolism controlling gene polymorphism. The study data showed correlations of different gene alleles with adaptability to high physical loads. Subject to a pharmacological analysis under the study were the effects of Metaprot and Citoflavin on the athletes' functionality rates under extreme physical loads. Metaprot was found to improve the adaptation mechanisms under extreme loads both in the biochemical and organs-specific levels, with significant savings in the performance rehabilitation time. Citoflavin was also tested to be of positive effect on the bodily adaptation mechanisms, particularly in rehabilitation periods; with the rehabilitative effects of Citoflavin found the most expressed in the athletes tested with different combinations of homozygote alleles associated with the lower aerobic productivity rates. The study data and analyses give grounds to conclude that the actual effects of pharmacological agents of nootropic action are largely determined by the anaerobic metabolism controlling gene polymorphism.

KW - MOLECULAR GENETICS

KW - ENDURANCE

KW - FUNCTIONAL RESERVES

KW - PROFESSIONAL SELECTION

KW - EXTREME PHYSICAL LOADS

KW - ADAPTATION

KW - BIOCHEMICAL INDICATORS

UR - http://www.teoriya.ru/en/node/8716

M3 - Article

SP - 7

JO - THEORY AND PRACTICE OF PHYSICAL CULTURE

JF - THEORY AND PRACTICE OF PHYSICAL CULTURE

SN - 2409-4234

ER -