TY - JOUR

T1 - Principles of Calcium Signal Generation and Transduction in Plant Cells

AU - Medvedev, S. S.

PY - 2018/11/1

Y1 - 2018/11/1

N2 - Calcium ions exhibit unique properties and a universal ability to transmit diverse signals in plant cells under the primary action of hormones, pathogens, light, gravity, and various abiotic stressors. In the last few years, considerable progress has been achieved in deciphering the mechanisms of Ca2+ involvement in the regulation of plant responses. Recent studies revealed the genes encoding Ca2+-permeable channels that conduct Ca2+ currents across the membranes during the transduction of the Ca2+ signal. These proteins comprise the ligand-gated Ca2+-permeable channels activated by cyclic nucleotides (CNGC) and amino acids (glutamate receptor-like channels, GLR), the voltage-gated tonoplast channel (two-pore channel, TPC1), mechanosensitive channels (MSL, MCA, OSCA1), and annexins. The role of Ca2+-ATPase and Ca2+/H+-exchangers in the active extrusion of excess cytoplasmic Ca2+ into the apoplast or cell organelles was examined in detail. The calmodulins (CaM), CaM-like proteins (CML), Ca2+-dependent protein kinases (CDPK), and complexes of calcineurin-B-like proteins (CBL) with CBL-interacting protein kinases (CIPK) were found to produce intricate signaling networks that decode Ca2+ signals and elicit plant responses to external stimuli. This review analyzes the data accumulated over the past decade on the principles of formation and propagation of the calcium signal in plant cells.

AB - Calcium ions exhibit unique properties and a universal ability to transmit diverse signals in plant cells under the primary action of hormones, pathogens, light, gravity, and various abiotic stressors. In the last few years, considerable progress has been achieved in deciphering the mechanisms of Ca2+ involvement in the regulation of plant responses. Recent studies revealed the genes encoding Ca2+-permeable channels that conduct Ca2+ currents across the membranes during the transduction of the Ca2+ signal. These proteins comprise the ligand-gated Ca2+-permeable channels activated by cyclic nucleotides (CNGC) and amino acids (glutamate receptor-like channels, GLR), the voltage-gated tonoplast channel (two-pore channel, TPC1), mechanosensitive channels (MSL, MCA, OSCA1), and annexins. The role of Ca2+-ATPase and Ca2+/H+-exchangers in the active extrusion of excess cytoplasmic Ca2+ into the apoplast or cell organelles was examined in detail. The calmodulins (CaM), CaM-like proteins (CML), Ca2+-dependent protein kinases (CDPK), and complexes of calcineurin-B-like proteins (CBL) with CBL-interacting protein kinases (CIPK) were found to produce intricate signaling networks that decode Ca2+ signals and elicit plant responses to external stimuli. This review analyzes the data accumulated over the past decade on the principles of formation and propagation of the calcium signal in plant cells.

KW - Ca-ATPases

KW - Ca-binding sensor proteins

KW - Ca-permeable channels

KW - Ca/H-exchangers

KW - calcium

KW - calcium signaling

KW - calcium spikes

KW - oscillations

KW - plants

KW - signal transduction

KW - waves

KW - Ca 2+-permeable channels

KW - Ca 2+ /H +-exchang-ers

KW - Ca 2+-binding sensor proteins

KW - and oscillations

KW - Ca 2+-ATPases

KW - ARABIDOPSIS-THALIANA

KW - NUCLEOTIDE GATED CHANNELS

KW - CYTOSOLIC CA2+

KW - DEPENDENT PROTEIN-KINASE

KW - PLASMA-MEMBRANE

KW - Ca2+-binding sensor proteins

KW - GENE-EXPRESSION

KW - H+-exchangers

KW - NADPH OXIDASE

KW - OSMOTIC-STRESS

KW - DECODING MECHANISMS

KW - Ca2+

KW - Ca2+-ATPases

KW - Ca2+-permeable channels

KW - ION CHANNELS

UR - http://www.scopus.com/inward/record.url?scp=85056309552&partnerID=8YFLogxK

UR - https://link.springer.com/content/pdf/10.1134%2FS1021443718060109.pdf

UR - http://www.mendeley.com/research/principles-calcium-signal-generation-transduction-plant-cells

U2 - 10.1134/S1021443718060109

DO - 10.1134/S1021443718060109

M3 - Review article

AN - SCOPUS:85056309552

VL - 65

SP - 771

EP - 783

JO - Russian Journal of Plant Physiology

JF - Russian Journal of Plant Physiology

SN - 1021-4437

IS - 6

ER -