Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Preparation for the in vitro fertilization treatment of infertility in diminished ovarian reserve– pre-IVF tidor. / Vartanyan, Emma Vramovna; Tsaturova, Kristina Ashotovna; Devyatova, Ekaterina Aleksandrovna; Mikhailyukova, A. S.; Levin, V. A.; Sagamonova, K. Yu; Gromenko, D. S.; Ovsyannikova, T. V.; Erlikhman, N. M.; Kolosova, E. A.; Safronova, E. V.; Fotina, O. V.; Krasnovskaya, E. V.; Pozharischenskaya, T. G.; Autleva, S. R.; Gzgzyan, A. M.; Nuriev, I. R.; Voropaeva, E. E.; Pestova, T. I.; Zdanovsky, V. M.; Kim, N. A.; Kotelnikov, A. N.; Safronov, O. V.; Nazarenko, T. A.; Ionova, R. M.
в: Akusherstvo i Ginekologiya (Russian Federation), Том 2019, № 8, 2019, стр. 134-142.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
}
TY - JOUR
T1 - Preparation for the in vitro fertilization treatment of infertility in diminished ovarian reserve– pre-IVF tidor
AU - Vartanyan, Emma Vramovna
AU - Tsaturova, Kristina Ashotovna
AU - Devyatova, Ekaterina Aleksandrovna
AU - Mikhailyukova, A. S.
AU - Levin, V. A.
AU - Sagamonova, K. Yu
AU - Gromenko, D. S.
AU - Ovsyannikova, T. V.
AU - Erlikhman, N. M.
AU - Kolosova, E. A.
AU - Safronova, E. V.
AU - Fotina, O. V.
AU - Krasnovskaya, E. V.
AU - Pozharischenskaya, T. G.
AU - Autleva, S. R.
AU - Gzgzyan, A. M.
AU - Nuriev, I. R.
AU - Voropaeva, E. E.
AU - Pestova, T. I.
AU - Zdanovsky, V. M.
AU - Kim, N. A.
AU - Kotelnikov, A. N.
AU - Safronov, O. V.
AU - Nazarenko, T. A.
AU - Ionova, R. M.
N1 - Publisher Copyright: © 2019, Bionika Media Ltd.. All rights reserved. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2019
Y1 - 2019
N2 - Objective. To assess the quality of oocytes, embryos, and outcomes of in vitro fertilization (IVF) cycles in patients with diminished ovarian reserve (OR) who received inositol before infertility treatment. Subjects and methods. An observational comparative multicenter study pre-IVF TIDOR included 270 patients. Group 1 (n=158) took inositol 4000 mg + folic acid 400 μg (Inofert, Italfarmaco S.p.A., Italy); Group 2 (n=112) did not receive inositol before infertility treatment using IVF. The inclusion criteria were age <38 years; a history of ovarian surgery; AMH <1.0 pg/ml, transfer of ≤2 embryos (ET) in the ovarian stimulation (OS) cycle. Results. In Group 1 and Group 2, mature oocytes (n=5 (0–7) and 2 (0–5); p = 0.049) and good-quality embryos (42.2 and 30.1%; p = 0.049) were retrieved; there was a high rate of ET-induced pregnancy (38.1and 30.0%; p = 0.041). Conclusion. It is expedient to use inositol (Inofert, Italfarmaco S.p.A., Italy) in women younger than 38 years after ovarian surgery in order to enhance the efficiency of IVF.
AB - Objective. To assess the quality of oocytes, embryos, and outcomes of in vitro fertilization (IVF) cycles in patients with diminished ovarian reserve (OR) who received inositol before infertility treatment. Subjects and methods. An observational comparative multicenter study pre-IVF TIDOR included 270 patients. Group 1 (n=158) took inositol 4000 mg + folic acid 400 μg (Inofert, Italfarmaco S.p.A., Italy); Group 2 (n=112) did not receive inositol before infertility treatment using IVF. The inclusion criteria were age <38 years; a history of ovarian surgery; AMH <1.0 pg/ml, transfer of ≤2 embryos (ET) in the ovarian stimulation (OS) cycle. Results. In Group 1 and Group 2, mature oocytes (n=5 (0–7) and 2 (0–5); p = 0.049) and good-quality embryos (42.2 and 30.1%; p = 0.049) were retrieved; there was a high rate of ET-induced pregnancy (38.1and 30.0%; p = 0.041). Conclusion. It is expedient to use inositol (Inofert, Italfarmaco S.p.A., Italy) in women younger than 38 years after ovarian surgery in order to enhance the efficiency of IVF.
KW - In vitro fertilization
KW - Infertility
KW - Inositol
KW - Myo-inositol
KW - Ovarian reserve diminution
KW - Pregnancy
UR - http://www.scopus.com/inward/record.url?scp=85074536293&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85074536293
VL - 2019
SP - 134
EP - 142
JO - АКУШЕРСТВО И ГИНЕКОЛОГИЯ
JF - АКУШЕРСТВО И ГИНЕКОЛОГИЯ
SN - 0300-9092
IS - 8
ER -
ID: 76494302