The paper presents novel data on concentration and temperature dependences of density (rho), viscosity (eta), nanoparticle dimensions of the C-60-L-arginine derivative in aqueous solutions. Moreover, the binding of the Ca-60-L-arginine with human serum albumin (HSA) and radical scavenging activity of the C-60-L-arginine derivative in reaction with diphenylpicrylhydrazyl (DPPH) were studied. The structural characteristics of the C-60-Arg-water binary system were obtained on the basis of molecular dynamics method. (C) 2019 Elsevier B.V. All rights reserved.