TY - JOUR

T1 - Polyoxometalate-based peroxidase-like nanozymes

AU - Liu, Xiangwei

AU - Sun, Tiedong

AU - Sun, Yuan

AU - Manshina, Alina

AU - Wang, Lei

PY - 2024/3/22

Y1 - 2024/3/22

N2 - Nanozymes, as a new generation of artificial enzymes, exhibit similar chemical properties, catalytic efficiency, and reaction kinetics to natural enzymes. Nanozymes can offer several advantages over natural enzymes, including the decreased cost, the increased stability, and the enhanced catalytic activity. These advantages have positioned nanozymes as a research focus in the fields of chemistry, materials and biomedicine. Polyoxometalates (POMs) and their composites have been found to possess excellent catalytic capabilities as peroxidase mimics. Given this, this review aims to provide a comprehensive overview of the POM-based nanozymes, covering their structural categorization, evolution, and various applications over the past decade. The dynamic nature of this field would promise the intriguing challenges and opportunities in the future. Additionally, we address the existing issues with the POM-based peroxidase-like enzymes and suggest the potential directions for future research. This review would serve as a valuable resource for researchers seeking to develop the improved therapeutic and diagnostic technologies using the POM-based nanozymes, thereby advancing the fields of biochemistry and materials science.

AB - Nanozymes, as a new generation of artificial enzymes, exhibit similar chemical properties, catalytic efficiency, and reaction kinetics to natural enzymes. Nanozymes can offer several advantages over natural enzymes, including the decreased cost, the increased stability, and the enhanced catalytic activity. These advantages have positioned nanozymes as a research focus in the fields of chemistry, materials and biomedicine. Polyoxometalates (POMs) and their composites have been found to possess excellent catalytic capabilities as peroxidase mimics. Given this, this review aims to provide a comprehensive overview of the POM-based nanozymes, covering their structural categorization, evolution, and various applications over the past decade. The dynamic nature of this field would promise the intriguing challenges and opportunities in the future. Additionally, we address the existing issues with the POM-based peroxidase-like enzymes and suggest the potential directions for future research. This review would serve as a valuable resource for researchers seeking to develop the improved therapeutic and diagnostic technologies using the POM-based nanozymes, thereby advancing the fields of biochemistry and materials science.

KW - H2O2

KW - Nanomaterials

KW - Nanozymes

KW - Polyoxometalates, Peroxidase

UR - https://www.mendeley.com/catalogue/9129e5e3-5d76-3bbd-b86c-c695af5f640c/

U2 - 10.1016/j.nanoms.2024.03.002

DO - 10.1016/j.nanoms.2024.03.002

M3 - Article

JO - Nano Materials Science

JF - Nano Materials Science

SN - 2096-6482

ER -