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Polymorphisms of matrix metalloproteases 2 and 9 genes in ascending aorta aneurism patients. / Gavrilyuk, N.D.; Irtyuga, O.B.; Druzhkova, T.A.; Uspensky, V.E.; Malashicheva, A.B.; Kostareva, A.A.; Moiseeva, O.M.

в: РОССИЙСКИЙ КАРДИОЛОГИЧЕСКИЙ ЖУРНАЛ (Russian Journal of Cardiology), № 10, 2015, стр. 65-69.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Gavrilyuk, ND, Irtyuga, OB, Druzhkova, TA, Uspensky, VE, Malashicheva, AB, Kostareva, AA & Moiseeva, OM 2015, 'Polymorphisms of matrix metalloproteases 2 and 9 genes in ascending aorta aneurism patients', РОССИЙСКИЙ КАРДИОЛОГИЧЕСКИЙ ЖУРНАЛ (Russian Journal of Cardiology), № 10, стр. 65-69. https://doi.org/10.15829/1560-4071-2015-10-65-69

APA

Gavrilyuk, N. D., Irtyuga, O. B., Druzhkova, T. A., Uspensky, V. E., Malashicheva, A. B., Kostareva, A. A., & Moiseeva, O. M. (2015). Polymorphisms of matrix metalloproteases 2 and 9 genes in ascending aorta aneurism patients. РОССИЙСКИЙ КАРДИОЛОГИЧЕСКИЙ ЖУРНАЛ (Russian Journal of Cardiology), (10), 65-69. https://doi.org/10.15829/1560-4071-2015-10-65-69

Vancouver

Gavrilyuk ND, Irtyuga OB, Druzhkova TA, Uspensky VE, Malashicheva AB, Kostareva AA и пр. Polymorphisms of matrix metalloproteases 2 and 9 genes in ascending aorta aneurism patients. РОССИЙСКИЙ КАРДИОЛОГИЧЕСКИЙ ЖУРНАЛ (Russian Journal of Cardiology). 2015;(10):65-69. https://doi.org/10.15829/1560-4071-2015-10-65-69

Author

Gavrilyuk, N.D. ; Irtyuga, O.B. ; Druzhkova, T.A. ; Uspensky, V.E. ; Malashicheva, A.B. ; Kostareva, A.A. ; Moiseeva, O.M. / Polymorphisms of matrix metalloproteases 2 and 9 genes in ascending aorta aneurism patients. в: РОССИЙСКИЙ КАРДИОЛОГИЧЕСКИЙ ЖУРНАЛ (Russian Journal of Cardiology). 2015 ; № 10. стр. 65-69.

BibTeX

@article{f94a589f3a7a47c4bdf28634a3391ddb,
title = "Polymorphisms of matrix metalloproteases 2 and 9 genes in ascending aorta aneurism patients",
abstract = "{\textcopyright} 2015, Silicea-Poligraf. All Rights Reserved.Aim. To study the role of mononucleotide polymorphisms of the matrix metalloproteases genes MMP2 and MMP9 in the development of ascending aorta aneurism (AOA). Material and methods. Totally 287 patients included with AOA and 227 persons of control group. All patients underwent echocardiography and assessment of mononucleotide gene polymorphisms of MMP2 (rs2285053) and MMP9 (rs11697325, rs2274755, rs17577) real-time, by PCR. Results. The association of MMP9 (rs11697325) is confirmed for the formation of AOA. AA genotype was significantly more prevalent among AOA patients (χ2=7,2; p=0,01). AA genotype carriers had higher ascending aorta diameter comparing to other persons with different variants (p=0,02). The relation is shown of the polymorphism MMP2 (rs2285053) and AOA development. Persons with CC genotype were more prevalent in the group of the aorta pathology patients (χ2=7,0; p=0,03). Conclusion. Genetic variants MMP9 and MMP2 can be additional risk factors of",
author = "N.D. Gavrilyuk and O.B. Irtyuga and T.A. Druzhkova and V.E. Uspensky and A.B. Malashicheva and A.A. Kostareva and O.M. Moiseeva",
year = "2015",
doi = "10.15829/1560-4071-2015-10-65-69",
language = "русский",
pages = "65--69",
journal = " РОССИЙСКИЙ КАРДИОЛОГИЧЕСКИЙ ЖУРНАЛ",
issn = "1560-4071",
publisher = "Russian Society of Cardiology",
number = "10",

}

RIS

TY - JOUR

T1 - Polymorphisms of matrix metalloproteases 2 and 9 genes in ascending aorta aneurism patients

AU - Gavrilyuk, N.D.

AU - Irtyuga, O.B.

AU - Druzhkova, T.A.

AU - Uspensky, V.E.

AU - Malashicheva, A.B.

AU - Kostareva, A.A.

AU - Moiseeva, O.M.

PY - 2015

Y1 - 2015

N2 - © 2015, Silicea-Poligraf. All Rights Reserved.Aim. To study the role of mononucleotide polymorphisms of the matrix metalloproteases genes MMP2 and MMP9 in the development of ascending aorta aneurism (AOA). Material and methods. Totally 287 patients included with AOA and 227 persons of control group. All patients underwent echocardiography and assessment of mononucleotide gene polymorphisms of MMP2 (rs2285053) and MMP9 (rs11697325, rs2274755, rs17577) real-time, by PCR. Results. The association of MMP9 (rs11697325) is confirmed for the formation of AOA. AA genotype was significantly more prevalent among AOA patients (χ2=7,2; p=0,01). AA genotype carriers had higher ascending aorta diameter comparing to other persons with different variants (p=0,02). The relation is shown of the polymorphism MMP2 (rs2285053) and AOA development. Persons with CC genotype were more prevalent in the group of the aorta pathology patients (χ2=7,0; p=0,03). Conclusion. Genetic variants MMP9 and MMP2 can be additional risk factors of

AB - © 2015, Silicea-Poligraf. All Rights Reserved.Aim. To study the role of mononucleotide polymorphisms of the matrix metalloproteases genes MMP2 and MMP9 in the development of ascending aorta aneurism (AOA). Material and methods. Totally 287 patients included with AOA and 227 persons of control group. All patients underwent echocardiography and assessment of mononucleotide gene polymorphisms of MMP2 (rs2285053) and MMP9 (rs11697325, rs2274755, rs17577) real-time, by PCR. Results. The association of MMP9 (rs11697325) is confirmed for the formation of AOA. AA genotype was significantly more prevalent among AOA patients (χ2=7,2; p=0,01). AA genotype carriers had higher ascending aorta diameter comparing to other persons with different variants (p=0,02). The relation is shown of the polymorphism MMP2 (rs2285053) and AOA development. Persons with CC genotype were more prevalent in the group of the aorta pathology patients (χ2=7,0; p=0,03). Conclusion. Genetic variants MMP9 and MMP2 can be additional risk factors of

U2 - 10.15829/1560-4071-2015-10-65-69

DO - 10.15829/1560-4071-2015-10-65-69

M3 - статья

SP - 65

EP - 69

JO - РОССИЙСКИЙ КАРДИОЛОГИЧЕСКИЙ ЖУРНАЛ

JF - РОССИЙСКИЙ КАРДИОЛОГИЧЕСКИЙ ЖУРНАЛ

SN - 1560-4071

IS - 10

ER -

ID: 4008470