TY - JOUR

T1 - Plant stem cells

T2 - Unity and diversity

AU - Dodueva, I. E.

AU - Tvorogova, V. E.

AU - Azarakhsh, M.

AU - Lebedeva, M. A.

AU - Lutova, L. A.

N1 - Funding Information: The research on the mechanisms of maintaining plant SCs is supported by the Russian Foundation for Basic Research, grants 15-34-20071, 15-29-02737, and 14-04-00591, and the Russian Science Foundation, grant 16-16-10011. Publisher Copyright: © 2017, Pleiades Publishing, Ltd. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.

PY - 2017/6/1

Y1 - 2017/6/1

N2 - Stem cells (SCs) are undifferentiated cells of multicellular organisms that can divide, self-renew, and differentiate. Despite the differences in their properties, the general principles of the existence of SCs can be distinguished in all multicellular organisms. In plants, SCs are found in meristems, structures that ensure the continuous growth of a plant and provide material for the formation of various specialized tissues. There are numerous types of meristems: shoot apical meristem (SAM) and root apical meristem (RAM), and lateral meristems (LMs) (procambium, cambium, and pericycle), as well as the so-called irregular meristems, developing under certain conditions (callus, meristems of symbiotic nodules, spontaneous and pathogen-induced tumors, etc.). Specific mechanisms of regulation, which are based on the interaction of plant hormones and the major groups of transcription factors, were identified for each meristem. The activity of meristems is determined by two opposing processes: proliferation and self-renewal of SCs in the central part of the meristem and differentiation of specialized cells in the periphery. WOX-CLAVATA systems are a regulatory component conservative for different meristems, which ensures the consistency of the composition of the meristem, as well as the balance of SC proliferation and differentiation. In this review, we consider the similarities and differences between the principles of the organization of SC niches in plants and animals, as well as in a variety of meristems of higher plants; special attention will be paid to the role of WOX-CLAVATA systems in maintaining meristems and their interaction with other meristem regulators.

AB - Stem cells (SCs) are undifferentiated cells of multicellular organisms that can divide, self-renew, and differentiate. Despite the differences in their properties, the general principles of the existence of SCs can be distinguished in all multicellular organisms. In plants, SCs are found in meristems, structures that ensure the continuous growth of a plant and provide material for the formation of various specialized tissues. There are numerous types of meristems: shoot apical meristem (SAM) and root apical meristem (RAM), and lateral meristems (LMs) (procambium, cambium, and pericycle), as well as the so-called irregular meristems, developing under certain conditions (callus, meristems of symbiotic nodules, spontaneous and pathogen-induced tumors, etc.). Specific mechanisms of regulation, which are based on the interaction of plant hormones and the major groups of transcription factors, were identified for each meristem. The activity of meristems is determined by two opposing processes: proliferation and self-renewal of SCs in the central part of the meristem and differentiation of specialized cells in the periphery. WOX-CLAVATA systems are a regulatory component conservative for different meristems, which ensures the consistency of the composition of the meristem, as well as the balance of SC proliferation and differentiation. In this review, we consider the similarities and differences between the principles of the organization of SC niches in plants and animals, as well as in a variety of meristems of higher plants; special attention will be paid to the role of WOX-CLAVATA systems in maintaining meristems and their interaction with other meristem regulators.

KW - apical meristems

KW - callus

KW - cambium

KW - CLE peptides

KW - LRR-kinases

KW - meristems

KW - nodules

KW - pericycle

KW - stem cells

KW - tumors

KW - WOX

UR - http://www.scopus.com/inward/record.url?scp=85037073678&partnerID=8YFLogxK

U2 - 10.1134/S2079059717040025

DO - 10.1134/S2079059717040025

M3 - Article

AN - SCOPUS:85037073678

VL - 7

SP - 385

EP - 403

JO - Russian Journal of Genetics: Applied Research

JF - Russian Journal of Genetics: Applied Research

SN - 2079-0597

IS - 4

ER -