Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Physicochemical study of water-soluble C60(OH)24 fullerenol. / Sharoyko, Vladimir V.; Ageev, Sergei V.; Meshcheriakov, Anatolii A.; Akentiev, Alexander V.; Noskov, Boris A.; Rakipov, Ilnaz T.; Charykov, Nikolay A.; Kulenova, Natalya A.; Shaimardanova, Botagoz K.; Podolsky, Nikita E.; Semenov, Konstantin N.
в: Journal of Molecular Liquids, Том 311, 113360, 01.08.2020.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Physicochemical study of water-soluble C60(OH)24 fullerenol
AU - Sharoyko, Vladimir V.
AU - Ageev, Sergei V.
AU - Meshcheriakov, Anatolii A.
AU - Akentiev, Alexander V.
AU - Noskov, Boris A.
AU - Rakipov, Ilnaz T.
AU - Charykov, Nikolay A.
AU - Kulenova, Natalya A.
AU - Shaimardanova, Botagoz K.
AU - Podolsky, Nikita E.
AU - Semenov, Konstantin N.
PY - 2020/8/1
Y1 - 2020/8/1
N2 - The article presents novel physicochemical data on C60(OH)24 aqueous solutions. Temperature and concentration dependencies of density (ρ) and speed of sound (u) and surface tension (γ) were obtained. Additionally, the study of human serum albumin (HSA) binding to C60(OH)24 fullerenol was conducted, and thermodynamic characteristics of C60(OH)24–HSA binding were calculated. The obtained values of a binding constant demonstrate that the complexes of C60(OH)24 with HSA are stable and HSA can perform transport functions in the bloodstream. Finally, excess thermodynamic functions of C60(OH)24–H2O binary system were calculated under the application of Virial Decomposition Asymmetric Model (VD-AS) and the boundaries of diffusion stability loss were determined. Aqueous solutions of C60(OH)20 are thermodynamically stable up to xdiff = 6.0 · 10−5. Further concentration increase leads to formation of third-order clusters with linear dimensions of thousands of nanometres and phase separation of the aqueous solution.
AB - The article presents novel physicochemical data on C60(OH)24 aqueous solutions. Temperature and concentration dependencies of density (ρ) and speed of sound (u) and surface tension (γ) were obtained. Additionally, the study of human serum albumin (HSA) binding to C60(OH)24 fullerenol was conducted, and thermodynamic characteristics of C60(OH)24–HSA binding were calculated. The obtained values of a binding constant demonstrate that the complexes of C60(OH)24 with HSA are stable and HSA can perform transport functions in the bloodstream. Finally, excess thermodynamic functions of C60(OH)24–H2O binary system were calculated under the application of Virial Decomposition Asymmetric Model (VD-AS) and the boundaries of diffusion stability loss were determined. Aqueous solutions of C60(OH)20 are thermodynamically stable up to xdiff = 6.0 · 10−5. Further concentration increase leads to formation of third-order clusters with linear dimensions of thousands of nanometres and phase separation of the aqueous solution.
KW - Density
KW - Excess thermodynamic functions
KW - Fullerenol
KW - HSA
KW - Speed of sound
KW - Surface tension
KW - DOXORUBICIN-INDUCED CARDIOTOXICITY
KW - ISOTHERMAL KINETICS
KW - RATS
KW - SYSTEMS
KW - SOLVENT
UR - http://www.scopus.com/inward/record.url?scp=85085164074&partnerID=8YFLogxK
U2 - 10.1016/j.molliq.2020.113360
DO - 10.1016/j.molliq.2020.113360
M3 - Article
AN - SCOPUS:85085164074
VL - 311
JO - Journal of Molecular Liquids
JF - Journal of Molecular Liquids
SN - 0167-7322
M1 - 113360
ER -
ID: 60314339