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Pd-Catalyzed Heteroannulation of Isoxazoles: Convergent Synthesis of Isoxazolo[5,4-c]quinolines. / Galenko, Ekaterina E. ; Zanakhov, Timur O. ; Novikov, Mikhail S. ; Khlebnikov, Alexander F. .
в: Tetrahedron Letters, Том 114, 154270, 2023.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Pd-Catalyzed Heteroannulation of Isoxazoles: Convergent Synthesis of Isoxazolo[5,4-c]quinolines
AU - Galenko, Ekaterina E.
AU - Zanakhov, Timur O.
AU - Novikov, Mikhail S.
AU - Khlebnikov, Alexander F.
PY - 2023
Y1 - 2023
N2 - Variously substituted isoxazolo[5,4-c]quinolines can be easily prepared in high yields by Pd-catalyzed heteroannulation of 5-carbonyl-4-haloisoxazoles with 2-aminophenylboronic acid derivatives. 4-Unsubstituted isoxazolo[5,4-c]quinolines can be readily modified at C4 via a chlorination/substitution sequence.
AB - Variously substituted isoxazolo[5,4-c]quinolines can be easily prepared in high yields by Pd-catalyzed heteroannulation of 5-carbonyl-4-haloisoxazoles with 2-aminophenylboronic acid derivatives. 4-Unsubstituted isoxazolo[5,4-c]quinolines can be readily modified at C4 via a chlorination/substitution sequence.
KW - heteroannulation
KW - Isoxazoles Isoxazolo[5,4-c]quinolines
KW - 2-Aminophenylboronic acid
KW - Pd-catalyzed coupling
KW - cross-coupling
KW - Cross-coupling
KW - Heteroannulation
KW - Pd-catalyzed
UR - https://www.mendeley.com/catalogue/29184668-e44c-3adb-9fef-80b016d219a6/
U2 - 10.1016/j.tetlet.2022.154270
DO - 10.1016/j.tetlet.2022.154270
M3 - Article
VL - 114
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
M1 - 154270
ER -
ID: 102205565