Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Selectivity of nitrene addition to the C[dbnd]C[sbnd]S[sbnd] fragment depends on the oxidative state of the sulfur atom as has been exemplified on various derivatives of 3,4-dihydro-2H-thiopyran under conditions of oxidative aminoaziridination. A unique structure with 2-thia-7-azabicyclo[4.1.0]heptane-2,2-dioxide core was obtained via addition of nitrene to the C[dbnd]C bond of thiopyran S,S-dioxide. For an unoxidized thiopyran, only en(phthaloyl)hydrazine resulted after cleavage of the initially formed aziridine. S-Oxide trapped the nitrene by the sulfur atom to form the sulfoximine leaving the double bond unaffected.
Язык оригинала | английский |
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Номер статьи | 153715 |
Журнал | Tetrahedron Letters |
Том | 94 |
DOI | |
Состояние | Опубликовано - 30 мар 2022 |
ID: 93941245