TY - JOUR

T1 - Overloading control of gas chromatographic systems

AU - Zenkevich, I.G.

AU - Pavlovskii, A.A.

PY - 2015

Y1 - 2015

N2 - Increasing the interlaboratory reproducibility of gas chromatographic retention indices requires avoiding measurements distorted by overloading effects. Several criteria of evaluating the limits of the mass overloading of gas chromatographic systems are compared and reconsidered. The criteria mostly appropriate for practical purposes are based on (i) the dependences of factors of peak broadening (ratio of peak height and its width) vs. amount of analyte injected into the chromatographic column and (ii) the dependence of parameters characterizing the peak distortion (asymmetry factor) vs. the amount of analyte. Both these criteria provide mutually comparable evaluations of the overloading limits for analytes of different polarity. At the same time, the dependence of retention indices vs. amounts of analyte injected in the chromatographic column cannot be recommended for overloading control, because the parameters of the corresponding linear regressions indicate temperature dependence. The interpretation of cer

AB - Increasing the interlaboratory reproducibility of gas chromatographic retention indices requires avoiding measurements distorted by overloading effects. Several criteria of evaluating the limits of the mass overloading of gas chromatographic systems are compared and reconsidered. The criteria mostly appropriate for practical purposes are based on (i) the dependences of factors of peak broadening (ratio of peak height and its width) vs. amount of analyte injected into the chromatographic column and (ii) the dependence of parameters characterizing the peak distortion (asymmetry factor) vs. the amount of analyte. Both these criteria provide mutually comparable evaluations of the overloading limits for analytes of different polarity. At the same time, the dependence of retention indices vs. amounts of analyte injected in the chromatographic column cannot be recommended for overloading control, because the parameters of the corresponding linear regressions indicate temperature dependence. The interpretation of cer

KW - Gas chromatography

KW - Overloading control

KW - Overloading criteria

U2 - 10.1002/jssc.201401471

DO - 10.1002/jssc.201401471

M3 - Article

VL - 38

SP - 2848

EP - 2856

JO - Journal of Separation Science

JF - Journal of Separation Science

SN - 1615-9306

IS - 16

ER -