Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Mismatch negativity (MMN) is a component of the auditory event-related brain potential which is widely used both in basic and clinical research. With the traditional oddball paradigm we obtained an MMN-like response that changed in duration of the silent gaps (standard 25 ms, deviant 50 ms and vice versa) in continuous auditory stimulation (1 kHz, 50 dB). To our knowledge, this is the first report of such a type of MMN. This response was compared to "classical" MMN elicited by duration change of sound of the same temporal characteristics. MMN in response to gap duration change differed in a shorter latency and had no polarity reversal at the mastoids. Both for sounds and gaps, when the deviant was longer than the standard, we observed a shorter latency of MMN response than in the reversed setup. We believe that use of the ERR and MMN techniques in a new paradigm of short gaps interrupting continuous sound stimulation might help to shed some light on the mechanisms of auditory information processing in the auditory system, as well as to bring deeper insight in understanding of MMN nature itself, and, possibly, to find some new clinical or fundamental applications.
Язык оригинала | русский |
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Страницы (с-по) | 998-1006 |
Число страниц | 9 |
Журнал | Rossiǐskii fiziologicheskiǐ zhurnal imeni I.M. Sechenova / Rossiǐskaia akademiia nauk |
Том | 95 |
Номер выпуска | 9 |
Состояние | Опубликовано - сен 2009 |
ID: 18468457