We consider an oblique derivative problem for non-divergence parabolic equations with discontinuous in t coefficients in a half-space. We obtain weighted coercive estimates of solutions in anisotropic Sobolev spaces. We also give an application of this result to linear parabolic equations in a bounded domain. In particular, if the boundary is of class C1,δ, δ∈(0,1], then we present a coercive estimate of solutions in weighted anisotropic Sobolev spaces, where the weight is a power of the distance to the boundary.