Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Novel Cyanoarylporphyrazines with Triazole Groups at the Macrocycle Periphery as Potential Sensibilizers of Photodynamic Therapy and Optical Probes of Intracellular Viscosity. / Lermontova, S. A.; Grigoryev, I. S.; Peskova, N. N.; Balalaeva, I. V. ; Боярский, Вадим Павлович; Klapshina, L. G.
в: Russian Journal of General Chemistry, Том 88, № 11, 01.11.2018, стр. 2339-2346.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Novel Cyanoarylporphyrazines with Triazole Groups at the Macrocycle Periphery as Potential Sensibilizers of Photodynamic Therapy and Optical Probes of Intracellular Viscosity
AU - Lermontova, S. A.
AU - Grigoryev, I. S.
AU - Peskova, N. N.
AU - Balalaeva, I. V.
AU - Боярский, Вадим Павлович
AU - Klapshina, L. G.
N1 - Funding Information: This study was financially supported by the Ministry of Education and Science of Russian Federation (project no. 6.3099.2017) and Russian Science Foundation (project no. 18-73-00194).
PY - 2018/11/1
Y1 - 2018/11/1
N2 - Novel fluorescent dyes of the cyanoarylporphyrazine series containing peripheral triazole groups have been synthesized. Their photophysical properties and the local viscosity effect on the fluorescence have been studied. The experiments with cell cultures have revealed rapid accumulation of the dyes in the cells cytoplasm. Photo- and dark cytotoxicity of the compounds have been evaluated by means of the MTT test.
AB - Novel fluorescent dyes of the cyanoarylporphyrazine series containing peripheral triazole groups have been synthesized. Their photophysical properties and the local viscosity effect on the fluorescence have been studied. The experiments with cell cultures have revealed rapid accumulation of the dyes in the cells cytoplasm. Photo- and dark cytotoxicity of the compounds have been evaluated by means of the MTT test.
KW - порфиразины
KW - комплексы иттербия
KW - фотосенсибилизаторы
KW - оптические зонды
KW - внутриклеточная вязкость
KW - optical probes of intracellular viscosity
KW - photosensibilizers
KW - porphyrazines
KW - template synthesis
KW - ytterbium complexes
KW - PORPHYRAZINES
KW - PHOTOSENSITIZERS
KW - AGENTS
KW - PHTHALOCYANINES
KW - CELL
KW - DERIVATIVES
UR - http://www.scopus.com/inward/record.url?scp=85059146250&partnerID=8YFLogxK
U2 - 10.1134/S1070363218110154
DO - 10.1134/S1070363218110154
M3 - Article
VL - 88
SP - 2339
EP - 2346
JO - Russian Journal of General Chemistry
JF - Russian Journal of General Chemistry
SN - 1070-3632
IS - 11
ER -
ID: 36454831