The method of laser-induced metal deposition was applied to synthesize nano-and microstructured metal electrodes for non-enzymatic glucose and hydrogen peroxide sensing. These electrodes were characterized by SEM, EDX, SIMS, XRD and EIS. Copper electrodes have a linear dependence of the current-concentration in the range of 10-100 μmol/L for hydrogen peroxide and 0.6-3.0 mmol/L for D-glucose.