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New tetracyclic 1,4-oxazepines constructed via practically simple tandem condensation strategy from readily available synthons. / Sapegin, Alexander V.; Kalinin, Stanislav A. ; Smirnov, Alexey V.; Dorogov, Mikhail V.; Krasavin, Mikhail.

в: Tetrahedron, Том 70, № 5, 2014, стр. 1077-1083.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Sapegin, AV, Kalinin, SA, Smirnov, AV, Dorogov, MV & Krasavin, M 2014, 'New tetracyclic 1,4-oxazepines constructed via practically simple tandem condensation strategy from readily available synthons', Tetrahedron, Том. 70, № 5, стр. 1077-1083. https://doi.org/10.1016/j.tet.2013.12.026

APA

Sapegin, A. V., Kalinin, S. A., Smirnov, A. V., Dorogov, M. V., & Krasavin, M. (2014). New tetracyclic 1,4-oxazepines constructed via practically simple tandem condensation strategy from readily available synthons. Tetrahedron, 70(5), 1077-1083. https://doi.org/10.1016/j.tet.2013.12.026

Vancouver

Sapegin AV, Kalinin SA, Smirnov AV, Dorogov MV, Krasavin M. New tetracyclic 1,4-oxazepines constructed via practically simple tandem condensation strategy from readily available synthons. Tetrahedron. 2014;70(5):1077-1083. https://doi.org/10.1016/j.tet.2013.12.026

Author

Sapegin, Alexander V. ; Kalinin, Stanislav A. ; Smirnov, Alexey V. ; Dorogov, Mikhail V. ; Krasavin, Mikhail. / New tetracyclic 1,4-oxazepines constructed via practically simple tandem condensation strategy from readily available synthons. в: Tetrahedron. 2014 ; Том 70, № 5. стр. 1077-1083.

BibTeX

@article{5d1f5d74ca2a4295bbce0cf27dee8f04,
title = "New tetracyclic 1,4-oxazepines constructed via practically simple tandem condensation strategy from readily available synthons",
abstract = "A streamlined synthetic methodology towards novel tetracyclic 1,4-oxazepines from readily available precursors is described. The compounds, designed as more soluble version of the earlier described, poorly soluble dibenzo[bf][1,4]oxazepines, were obtained in high yields and as a single regioisomer as a result of three tandem chemical events-nucleophilic aromatic substitution, Smiles rearrangement and denitrocyclization. (C) 2014 Elsevier Ltd. All rights reserved.",
keywords = "Bioisosteres, Solubilizing groups, Oxazepines, Tetracyclic, Privileged structures, Nucleophilic aromatic substitution, Smiles rearrangement, Denitrocyclization, POTENT, DENITROCYCLIZATION, ANTAGONISTS, INHIBITORS, ANALOGS",
author = "Sapegin, {Alexander V.} and Kalinin, {Stanislav A.} and Smirnov, {Alexey V.} and Dorogov, {Mikhail V.} and Mikhail Krasavin",
year = "2014",
doi = "10.1016/j.tet.2013.12.026",
language = "Английский",
volume = "70",
pages = "1077--1083",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Elsevier",
number = "5",

}

RIS

TY - JOUR

T1 - New tetracyclic 1,4-oxazepines constructed via practically simple tandem condensation strategy from readily available synthons

AU - Sapegin, Alexander V.

AU - Kalinin, Stanislav A.

AU - Smirnov, Alexey V.

AU - Dorogov, Mikhail V.

AU - Krasavin, Mikhail

PY - 2014

Y1 - 2014

N2 - A streamlined synthetic methodology towards novel tetracyclic 1,4-oxazepines from readily available precursors is described. The compounds, designed as more soluble version of the earlier described, poorly soluble dibenzo[bf][1,4]oxazepines, were obtained in high yields and as a single regioisomer as a result of three tandem chemical events-nucleophilic aromatic substitution, Smiles rearrangement and denitrocyclization. (C) 2014 Elsevier Ltd. All rights reserved.

AB - A streamlined synthetic methodology towards novel tetracyclic 1,4-oxazepines from readily available precursors is described. The compounds, designed as more soluble version of the earlier described, poorly soluble dibenzo[bf][1,4]oxazepines, were obtained in high yields and as a single regioisomer as a result of three tandem chemical events-nucleophilic aromatic substitution, Smiles rearrangement and denitrocyclization. (C) 2014 Elsevier Ltd. All rights reserved.

KW - Bioisosteres

KW - Solubilizing groups

KW - Oxazepines

KW - Tetracyclic

KW - Privileged structures

KW - Nucleophilic aromatic substitution

KW - Smiles rearrangement

KW - Denitrocyclization

KW - POTENT

KW - DENITROCYCLIZATION

KW - ANTAGONISTS

KW - INHIBITORS

KW - ANALOGS

U2 - 10.1016/j.tet.2013.12.026

DO - 10.1016/j.tet.2013.12.026

M3 - статья

VL - 70

SP - 1077

EP - 1083

JO - Tetrahedron

JF - Tetrahedron

SN - 0040-4020

IS - 5

ER -

ID: 5708291