Standard

New supramolecular AuI-CuI complex as potential luminescent label for proteins. / Krupenya, D.V.; Snegurov, P.A.; Grachova, E.V.; Gurzhiy, V.V.; Tunik, S.P.; Melnikov, A.S.; Serdobintsev, P.Y.; Vlakh, E.G.; Sinitsyna, E.S.; Tennikova, T.B.

в: Inorganic Chemistry, Том 52, № 21, 2013, стр. 12521-12528.

Результаты исследований: Научные публикации в периодических изданиях › статья

Harvard

Krupenya, DV, Snegurov, PA, Grachova, EV, Gurzhiy, VV, Tunik, SP, Melnikov, AS, Serdobintsev, PY, Vlakh, EG, Sinitsyna, ES & Tennikova, TB 2013, 'New supramolecular AuI-CuI complex as potential luminescent label for proteins', Inorganic Chemistry, Том. 52, № 21, стр. 12521-12528. https://doi.org/10.1021/ic401569n

APA

Krupenya, D. V., Snegurov, P. A., Grachova, E. V., Gurzhiy, V. V., Tunik, S. P., Melnikov, A. S., Serdobintsev, P. Y., Vlakh, E. G., Sinitsyna, E. S., & Tennikova, T. B. (2013). New supramolecular AuI-CuI complex as potential luminescent label for proteins. Inorganic Chemistry, 52(21), 12521-12528. https://doi.org/10.1021/ic401569n

Vancouver

Krupenya DV, Snegurov PA, Grachova EV, Gurzhiy VV, Tunik SP, Melnikov AS и пр. New supramolecular AuI-CuI complex as potential luminescent label for proteins. Inorganic Chemistry. 2013;52(21):12521-12528. https://doi.org/10.1021/ic401569n

Author

Krupenya, D.V. ; Snegurov, P.A. ; Grachova, E.V. ; Gurzhiy, V.V. ; Tunik, S.P. ; Melnikov, A.S. ; Serdobintsev, P.Y. ; Vlakh, E.G. ; Sinitsyna, E.S. ; Tennikova, T.B. / New supramolecular AuI-CuI complex as potential luminescent label for proteins. в: Inorganic Chemistry. 2013 ; Том 52, № 21. стр. 12521-12528.

BibTeX

@article{094803bd612b4406a0e471da4a4fcf8e,
title = "New supramolecular AuI-CuI complex as potential luminescent label for proteins",
abstract = "A novel supramolecular [Au6Cu2(C2C6H4-4-COONC4H4O2)6(Ph2PC6H4PPh2)3](PF6)2 complex functionalized with succinimide alkynyl substituent has been synthesized and characterized using X-ray crystallography, mass spectrometry and NMR spectroscopy. Like the other complexes of this class demonstrates bright emission in acetone and dichloromethane solutions with the excited state lifetime in microsecond domain. This complex readily reacts with surface amine group of proteins/enzymes (human serum albumin, rabbit anti-HSA antibodies, α-chymotrypsin) to give covalent conjugates, which contain up to five molecules of the luminescent label bound to the biomolecule. The conjugates keep high level of the phosphorescent label emission but in contrast to the parent complex molecule display excellent solubility and high stability in physiological media. Investigation of biological activity of the conjugates also showed that specific structure of the biomolecules remains nearly unchanged upon bonding with the label that is indi",
keywords = "Phosphorescent label, Proteins, Bioconjugates, Supramolecular complexes, Gold",
author = "D.V. Krupenya and P.A. Snegurov and E.V. Grachova and V.V. Gurzhiy and S.P. Tunik and A.S. Melnikov and P.Y. Serdobintsev and E.G. Vlakh and E.S. Sinitsyna and T.B. Tennikova",
year = "2013",
doi = "10.1021/ic401569n",
language = "English",
volume = "52",
pages = "12521--12528",
journal = "Inorganic Chemistry",
issn = "0020-1669",
publisher = "American Chemical Society",
number = "21",

}

RIS

TY - JOUR

T1 - New supramolecular AuI-CuI complex as potential luminescent label for proteins

AU - Krupenya, D.V.

AU - Snegurov, P.A.

AU - Grachova, E.V.

AU - Gurzhiy, V.V.

AU - Tunik, S.P.

AU - Melnikov, A.S.

AU - Serdobintsev, P.Y.

AU - Vlakh, E.G.

AU - Sinitsyna, E.S.

AU - Tennikova, T.B.

PY - 2013

Y1 - 2013

N2 - A novel supramolecular [Au6Cu2(C2C6H4-4-COONC4H4O2)6(Ph2PC6H4PPh2)3](PF6)2 complex functionalized with succinimide alkynyl substituent has been synthesized and characterized using X-ray crystallography, mass spectrometry and NMR spectroscopy. Like the other complexes of this class demonstrates bright emission in acetone and dichloromethane solutions with the excited state lifetime in microsecond domain. This complex readily reacts with surface amine group of proteins/enzymes (human serum albumin, rabbit anti-HSA antibodies, α-chymotrypsin) to give covalent conjugates, which contain up to five molecules of the luminescent label bound to the biomolecule. The conjugates keep high level of the phosphorescent label emission but in contrast to the parent complex molecule display excellent solubility and high stability in physiological media. Investigation of biological activity of the conjugates also showed that specific structure of the biomolecules remains nearly unchanged upon bonding with the label that is indi

AB - A novel supramolecular [Au6Cu2(C2C6H4-4-COONC4H4O2)6(Ph2PC6H4PPh2)3](PF6)2 complex functionalized with succinimide alkynyl substituent has been synthesized and characterized using X-ray crystallography, mass spectrometry and NMR spectroscopy. Like the other complexes of this class demonstrates bright emission in acetone and dichloromethane solutions with the excited state lifetime in microsecond domain. This complex readily reacts with surface amine group of proteins/enzymes (human serum albumin, rabbit anti-HSA antibodies, α-chymotrypsin) to give covalent conjugates, which contain up to five molecules of the luminescent label bound to the biomolecule. The conjugates keep high level of the phosphorescent label emission but in contrast to the parent complex molecule display excellent solubility and high stability in physiological media. Investigation of biological activity of the conjugates also showed that specific structure of the biomolecules remains nearly unchanged upon bonding with the label that is indi

KW - Phosphorescent label

KW - Proteins

KW - Bioconjugates

KW - Supramolecular complexes

KW - Gold

U2 - 10.1021/ic401569n

DO - 10.1021/ic401569n

M3 - Article

VL - 52

SP - 12521

EP - 12528

JO - Inorganic Chemistry

JF - Inorganic Chemistry

SN - 0020-1669

IS - 21

ER -

ID: 7377222