Результаты исследований: Научные публикации в периодических изданиях › Обзорная статья › Рецензирование
Neurosteroids and Depression. / Жуков, Д.А.; Виноградова, Екатерина Павловна.
в: Neurochemical Journal, Том 15, № 3, 15, 07.2021, стр. 240-246.Результаты исследований: Научные публикации в периодических изданиях › Обзорная статья › Рецензирование
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TY - JOUR
T1 - Neurosteroids and Depression
AU - Жуков, Д.А.
AU - Виноградова, Екатерина Павловна
PY - 2021/7
Y1 - 2021/7
N2 - Neurosteroids are steroids that rapidly alter neuronal excitability by interacting with cell surface receptors, mainly the GABA/A receptor complex. Neurosteroids are synthesized both in the central nervous system and in peripheral tissues, from which they enter the brain via systemic blood circulation. Neurosteroids may regulate emotional behavior, and may therefore be important in the development of the depressive disorders: major depression, post-traumatic stress disorder, premenstrual dysphoric disorder, and postpartum depression. Studies of neurosteroids offer potential new treatments of depressive disorders.
AB - Neurosteroids are steroids that rapidly alter neuronal excitability by interacting with cell surface receptors, mainly the GABA/A receptor complex. Neurosteroids are synthesized both in the central nervous system and in peripheral tissues, from which they enter the brain via systemic blood circulation. Neurosteroids may regulate emotional behavior, and may therefore be important in the development of the depressive disorders: major depression, post-traumatic stress disorder, premenstrual dysphoric disorder, and postpartum depression. Studies of neurosteroids offer potential new treatments of depressive disorders.
KW - neurosteroids, depression
KW - neurosteroids
KW - depression
KW - PREGNENOLONE-SULFATE
KW - NEUROACTIVE STEROIDS
KW - PLASMA-CONCENTRATIONS
KW - INVERSE MODULATION
KW - MAJOR DEPRESSION
KW - RODENT MODEL
KW - RECEPTOR
KW - STRESS
KW - RAT
KW - ALLOPREGNANOLONE
UR - https://www.mendeley.com/catalogue/5df5a675-8b38-3bce-9b80-fc6b9e737e7b/
U2 - 10.1134/S1819712421030144
DO - 10.1134/S1819712421030144
M3 - Review article
VL - 15
SP - 240
EP - 246
JO - Neurochemical Journal
JF - Neurochemical Journal
SN - 1819-7124
IS - 3
M1 - 15
ER -
ID: 85770973