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Neuropharmacology, pharmacogenetics and pharmacogenomics of aggression : The zebrafish model. / de Abreu, Murilo S.; Giacomini, Ana C.V.V.; Genario, Rafael; dos Santos, Bruna E.; da Rosa, Larissa G.; Demin, Konstantin A.; Wappler-Guzzetta, Edina A.; Kalueff, Allan V.

в: Pharmacological Research, Том 141, 03.2019, стр. 602-608.

Результаты исследований: Научные публикации в периодических изданиях › Обзорная статья › Рецензирование

Harvard

de Abreu, MS, Giacomini, ACVV, Genario, R, dos Santos, BE, da Rosa, LG, Demin, KA, Wappler-Guzzetta, EA & Kalueff, AV 2019, 'Neuropharmacology, pharmacogenetics and pharmacogenomics of aggression: The zebrafish model', Pharmacological Research, Том. 141, стр. 602-608. https://doi.org/10.1016/j.phrs.2019.01.044

APA

de Abreu, M. S., Giacomini, A. C. V. V., Genario, R., dos Santos, B. E., da Rosa, L. G., Demin, K. A., Wappler-Guzzetta, E. A., & Kalueff, A. V. (2019). Neuropharmacology, pharmacogenetics and pharmacogenomics of aggression: The zebrafish model. Pharmacological Research, 141, 602-608. https://doi.org/10.1016/j.phrs.2019.01.044

Vancouver

de Abreu MS, Giacomini ACVV, Genario R, dos Santos BE, da Rosa LG, Demin KA и пр. Neuropharmacology, pharmacogenetics and pharmacogenomics of aggression: The zebrafish model. Pharmacological Research. 2019 Март;141:602-608. https://doi.org/10.1016/j.phrs.2019.01.044

Author

de Abreu, Murilo S. ; Giacomini, Ana C.V.V. ; Genario, Rafael ; dos Santos, Bruna E. ; da Rosa, Larissa G. ; Demin, Konstantin A. ; Wappler-Guzzetta, Edina A. ; Kalueff, Allan V. / Neuropharmacology, pharmacogenetics and pharmacogenomics of aggression : The zebrafish model. в: Pharmacological Research. 2019 ; Том 141. стр. 602-608.

BibTeX

@article{9fc2da5ee4104e54b9d7b412f11eda85,
title = "Neuropharmacology, pharmacogenetics and pharmacogenomics of aggression: The zebrafish model",
abstract = "The zebrafish (Danio rerio) is increasingly utilized as a powerful new model organism in neurobehavioral research. Aggression is a common symptom of many CNS disorders, has some genetic determinants and can be modulated pharmacologically in humans and animal model species. Mounting evidence suggests zebrafish as a useful tool to study neurobiology of aggression, and its pharmacological and genetic regulation. Here, we discuss mechanisms of zebrafish aggression and their pharmacological, pharmacogenetic and pharmacogenomic models, as well as recent developments and existing challenges in this field. We also emphasize the growing utility of zebrafish models in translational neuropharmacological research of aggression, fostering future discoveries of potential therapeutic agents for aggressive behavior.",
keywords = "Aggression, Animal models, CNS, Epigenetics, Pharmacological modulation, DANIO-RERIO, DNA METHYLATION, NMDA RECEPTORS, BEHAVIOR, NEURAL BASIS, ADULT ZEBRAFISH, PREFRONTAL CORTEX, IMPULSIVE AGGRESSION, SOCIAL-INTERACTION, ANIMAL-MODELS",
author = "{de Abreu}, {Murilo S.} and Giacomini, {Ana C.V.V.} and Rafael Genario and {dos Santos}, {Bruna E.} and {da Rosa}, {Larissa G.} and Demin, {Konstantin A.} and Wappler-Guzzetta, {Edina A.} and Kalueff, {Allan V.}",
year = "2019",
month = mar,
doi = "10.1016/j.phrs.2019.01.044",
language = "English",
volume = "141",
pages = "602--608",
journal = "Pharmacological Research",
issn = "1043-6618",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Neuropharmacology, pharmacogenetics and pharmacogenomics of aggression

T2 - The zebrafish model

AU - de Abreu, Murilo S.

AU - Giacomini, Ana C.V.V.

AU - Genario, Rafael

AU - dos Santos, Bruna E.

AU - da Rosa, Larissa G.

AU - Demin, Konstantin A.

AU - Wappler-Guzzetta, Edina A.

AU - Kalueff, Allan V.

PY - 2019/3

Y1 - 2019/3

N2 - The zebrafish (Danio rerio) is increasingly utilized as a powerful new model organism in neurobehavioral research. Aggression is a common symptom of many CNS disorders, has some genetic determinants and can be modulated pharmacologically in humans and animal model species. Mounting evidence suggests zebrafish as a useful tool to study neurobiology of aggression, and its pharmacological and genetic regulation. Here, we discuss mechanisms of zebrafish aggression and their pharmacological, pharmacogenetic and pharmacogenomic models, as well as recent developments and existing challenges in this field. We also emphasize the growing utility of zebrafish models in translational neuropharmacological research of aggression, fostering future discoveries of potential therapeutic agents for aggressive behavior.

AB - The zebrafish (Danio rerio) is increasingly utilized as a powerful new model organism in neurobehavioral research. Aggression is a common symptom of many CNS disorders, has some genetic determinants and can be modulated pharmacologically in humans and animal model species. Mounting evidence suggests zebrafish as a useful tool to study neurobiology of aggression, and its pharmacological and genetic regulation. Here, we discuss mechanisms of zebrafish aggression and their pharmacological, pharmacogenetic and pharmacogenomic models, as well as recent developments and existing challenges in this field. We also emphasize the growing utility of zebrafish models in translational neuropharmacological research of aggression, fostering future discoveries of potential therapeutic agents for aggressive behavior.

KW - Aggression

KW - Animal models

KW - CNS

KW - Epigenetics

KW - Pharmacological modulation

KW - DANIO-RERIO

KW - DNA METHYLATION

KW - NMDA RECEPTORS

KW - BEHAVIOR

KW - NEURAL BASIS

KW - ADULT ZEBRAFISH

KW - PREFRONTAL CORTEX

KW - IMPULSIVE AGGRESSION

KW - SOCIAL-INTERACTION

KW - ANIMAL-MODELS

UR - http://www.scopus.com/inward/record.url?scp=85061312370&partnerID=8YFLogxK

UR - http://www.mendeley.com/research/neuropharmacology-pharmacogenetics-pharmacogenomics-aggression-zebrafish-model

U2 - 10.1016/j.phrs.2019.01.044

DO - 10.1016/j.phrs.2019.01.044

M3 - Review article

AN - SCOPUS:85061312370

VL - 141

SP - 602

EP - 608

JO - Pharmacological Research

JF - Pharmacological Research

SN - 1043-6618

ER -

ID: 39064574