Результаты исследований: Научные публикации в периодических изданиях › Обзорная статья › Рецензирование
Near-Infrared Fluorescence Imaging with Indocyanine Green for Robot-Assisted Partial Nephrectomy : A Systematic Review and Meta-Analysis. / Giulioni, Carlo; Mulawkar, Prashant Motiram; Castellani, Daniele; De Stefano, Virgilio; Nedbal, Carlotta; Gadzhiev, Nariman; Pirola, Giacomo Maria; Law, Yu Xi Terence; Wroclawski, Marcelo Langer; Keat, William Ong Lay; Tiong, Ho Yee; Somani, Bhaskar Kumar; Galosi, Andrea Benedetto; Gauhar, Vineet.
в: Cancers, Том 15, № 23, 24.11.2023.Результаты исследований: Научные публикации в периодических изданиях › Обзорная статья › Рецензирование
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TY - JOUR
T1 - Near-Infrared Fluorescence Imaging with Indocyanine Green for Robot-Assisted Partial Nephrectomy
T2 - A Systematic Review and Meta-Analysis
AU - Giulioni, Carlo
AU - Mulawkar, Prashant Motiram
AU - Castellani, Daniele
AU - De Stefano, Virgilio
AU - Nedbal, Carlotta
AU - Gadzhiev, Nariman
AU - Pirola, Giacomo Maria
AU - Law, Yu Xi Terence
AU - Wroclawski, Marcelo Langer
AU - Keat, William Ong Lay
AU - Tiong, Ho Yee
AU - Somani, Bhaskar Kumar
AU - Galosi, Andrea Benedetto
AU - Gauhar, Vineet
PY - 2023/11/24
Y1 - 2023/11/24
N2 - BACKGROUND: We aimed to analyze the influence of near-infrared fluorescence (NIRF) using indocyanine green (ICG) with standard robot-assisted partial nephrectomy (RAPN) in patients with a kidney tumor (KT).METHODS: We performed a literature search on 12 September 2023 through PubMed, EMBASE, and Scopus. The analysis included observational studies that examined the perioperative and long-term outcomes of patients with a KT who underwent RAPN with NIRF.RESULTS: Overall, eight prospective studies, involving 535 patients, were eligible for this meta-analysis, with 212 participants in the ICG group and 323 in the No ICG group. For warm ischemia time, the ICG group showed a lower duration (weighted Mean difference (WMD) = -2.05, 95% confidence interval (CI) = -3.30--0.80, p = 0.011). The postoperative eGFR also favored the ICG group (WMD = 7.67, 95% CI = 2.88-12.46, p = 0.002). No difference emerged for the other perioperative outcomes between the two groups. In terms of oncological radicality, the positive surgical margins and tumor recurrence rates were similar among the two groups.CONCLUSIONS: Our meta-analysis showed that NIRF with ICG during RAPN yields a favorable impact on functional outcomes, whereas it exerts no such influence on oncological aspects. Therefore, NIRF should be adopted when preserving nephron function is a paramount concern.
AB - BACKGROUND: We aimed to analyze the influence of near-infrared fluorescence (NIRF) using indocyanine green (ICG) with standard robot-assisted partial nephrectomy (RAPN) in patients with a kidney tumor (KT).METHODS: We performed a literature search on 12 September 2023 through PubMed, EMBASE, and Scopus. The analysis included observational studies that examined the perioperative and long-term outcomes of patients with a KT who underwent RAPN with NIRF.RESULTS: Overall, eight prospective studies, involving 535 patients, were eligible for this meta-analysis, with 212 participants in the ICG group and 323 in the No ICG group. For warm ischemia time, the ICG group showed a lower duration (weighted Mean difference (WMD) = -2.05, 95% confidence interval (CI) = -3.30--0.80, p = 0.011). The postoperative eGFR also favored the ICG group (WMD = 7.67, 95% CI = 2.88-12.46, p = 0.002). No difference emerged for the other perioperative outcomes between the two groups. In terms of oncological radicality, the positive surgical margins and tumor recurrence rates were similar among the two groups.CONCLUSIONS: Our meta-analysis showed that NIRF with ICG during RAPN yields a favorable impact on functional outcomes, whereas it exerts no such influence on oncological aspects. Therefore, NIRF should be adopted when preserving nephron function is a paramount concern.
U2 - https://doi.org/10.3390/cancers15235560
DO - https://doi.org/10.3390/cancers15235560
M3 - Review article
C2 - 38067266
VL - 15
JO - Cancers
JF - Cancers
SN - 2072-6694
IS - 23
ER -
ID: 116243341