TY - JOUR

T1 - Myxopapillary Ependymoma of Lumbar Soft Tissue

T2 - A Case Report With Gene Expression Evaluation

AU - Shelekhova, Ksenya V.

AU - Egorenkov, Vitaly V.

AU - Kheinstein, Valery A.

AU - Konstantinova, Anastasia M.

AU - Iyevleva, Aglaya

AU - Imyanitov, Evgeny N.

AU - Matsko, Marina V.

AU - Matsko, Dmitry E.

PY - 2018/6/1

Y1 - 2018/6/1

N2 - Primary extraspinal myxopapillary ependymoma (MPE) is an exceptionally rare lesion that is mainly located in the subcutaneous sacrococcygeal region. We describe the first case of MPE that presented as an intramuscular tumor mass located in the lumbar area. Absence of the visible connection with the spinal cord and lack of any other tumors in the reported case argue for the primary ectopic origin of the MPE. The differential diagnosis of MPE is discussed. Additionally, we evaluated the expression level of molecular biomarkers that have a prognostic value in central nervous system tumors.

AB - Primary extraspinal myxopapillary ependymoma (MPE) is an exceptionally rare lesion that is mainly located in the subcutaneous sacrococcygeal region. We describe the first case of MPE that presented as an intramuscular tumor mass located in the lumbar area. Absence of the visible connection with the spinal cord and lack of any other tumors in the reported case argue for the primary ectopic origin of the MPE. The differential diagnosis of MPE is discussed. Additionally, we evaluated the expression level of molecular biomarkers that have a prognostic value in central nervous system tumors.

KW - ectopic

KW - extraspinal

KW - gene expression

KW - lumbar

KW - myxopapillary ependymoma

KW - soft tissue

UR - http://www.scopus.com/inward/record.url?scp=85042070210&partnerID=8YFLogxK

U2 - 10.1177/1066896917748195

DO - 10.1177/1066896917748195

M3 - Article

C2 - 29254456

AN - SCOPUS:85042070210

VL - 26

SP - 364

EP - 369

JO - International Journal of Surgical Pathology

JF - International Journal of Surgical Pathology

SN - 1066-8969

IS - 4

ER -