Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Multilayered Particles Based on Biopolyelectrolytes as Potential Peptide Delivery Systems. / Zashikhina, N. N.; Yudin, D. V.; Tarasenko, I. I.; Osipova, O. M.; Korzhikova-Vlakh, E. G.
в: Polymer Science - Series A, Том 62, № 1, 01.2020, стр. 43-53.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
}
TY - JOUR
T1 - Multilayered Particles Based on Biopolyelectrolytes as Potential Peptide Delivery Systems
AU - Zashikhina, N. N.
AU - Yudin, D. V.
AU - Tarasenko, I. I.
AU - Osipova, O. M.
AU - Korzhikova-Vlakh, E. G.
N1 - Zashikhina, N.N., Yudin, D.V., Tarasenko, I.I. et al. Multilayered Particles Based on Biopolyelectrolytes as Potential Peptide Delivery Systems. Polym. Sci. Ser. A 62, 43–53 (2020). https://doi.org/10.1134/S0965545X20010125
PY - 2020/1
Y1 - 2020/1
N2 - Abstract: A series of amphiphilic charged copolymers of amino acids is synthesized, and their binding to cationic and anionic peptides is studied. The resulting interpolyelectrolyte complexes are additionally stabilized by cationic/anionic polysaccharides using surface layering. The positive effect of coatings on the release rate of peptides and decrease in the cytotoxicity and increase in the stability of the resulting peptide delivery systems in biological media is shown.
AB - Abstract: A series of amphiphilic charged copolymers of amino acids is synthesized, and their binding to cationic and anionic peptides is studied. The resulting interpolyelectrolyte complexes are additionally stabilized by cationic/anionic polysaccharides using surface layering. The positive effect of coatings on the release rate of peptides and decrease in the cytotoxicity and increase in the stability of the resulting peptide delivery systems in biological media is shown.
KW - BLOCK-COPOLYMER VESICLES
KW - IN-VITRO
KW - INSULIN
KW - NANOPARTICLES
KW - RELEASE
KW - KINETICS
UR - http://www.scopus.com/inward/record.url?scp=85082136700&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/7e6afc53-8ed9-3847-977d-a2edf9f85464/
U2 - 10.1134/S0965545X20010125
DO - 10.1134/S0965545X20010125
M3 - Article
AN - SCOPUS:85082136700
VL - 62
SP - 43
EP - 53
JO - Polymer Science - Series A
JF - Polymer Science - Series A
SN - 0965-545X
IS - 1
ER -
ID: 70742920