Standard

Multi-component reactions between 2-aminopyrimidine, aldehydes and isonitriles : The use of a nonpolar solvent suppresses formation of multiple products. / Parchinsky, Vladislav Z.; Shuvalova, Olga; Ushakova, Olga; Kravchenko, Dmitry V.; Krasavin, Mikhail.

в: Tetrahedron Letters, Том 47, № 6, 06.02.2006, стр. 947-951.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Parchinsky, VZ, Shuvalova, O, Ushakova, O, Kravchenko, DV & Krasavin, M 2006, 'Multi-component reactions between 2-aminopyrimidine, aldehydes and isonitriles: The use of a nonpolar solvent suppresses formation of multiple products', Tetrahedron Letters, Том. 47, № 6, стр. 947-951. https://doi.org/10.1016/j.tetlet.2005.11.152

APA

Parchinsky, V. Z., Shuvalova, O., Ushakova, O., Kravchenko, D. V., & Krasavin, M. (2006). Multi-component reactions between 2-aminopyrimidine, aldehydes and isonitriles: The use of a nonpolar solvent suppresses formation of multiple products. Tetrahedron Letters, 47(6), 947-951. https://doi.org/10.1016/j.tetlet.2005.11.152

Vancouver

Parchinsky VZ, Shuvalova O, Ushakova O, Kravchenko DV, Krasavin M. Multi-component reactions between 2-aminopyrimidine, aldehydes and isonitriles: The use of a nonpolar solvent suppresses formation of multiple products. Tetrahedron Letters. 2006 Февр. 6;47(6):947-951. https://doi.org/10.1016/j.tetlet.2005.11.152

Author

Parchinsky, Vladislav Z. ; Shuvalova, Olga ; Ushakova, Olga ; Kravchenko, Dmitry V. ; Krasavin, Mikhail. / Multi-component reactions between 2-aminopyrimidine, aldehydes and isonitriles : The use of a nonpolar solvent suppresses formation of multiple products. в: Tetrahedron Letters. 2006 ; Том 47, № 6. стр. 947-951.

BibTeX

@article{517778d4b93448d0882811f03b20e803,
title = "Multi-component reactions between 2-aminopyrimidine, aldehydes and isonitriles: The use of a nonpolar solvent suppresses formation of multiple products",
abstract = "A reliable and convenient protocol for MCRs between 2-aminopyrimidine, aldehydes and isonitriles is described. Toluene was chosen as the reaction solvent based on mechanistic reasoning. The product mixtures were found to contain a single imidazo[1,2-a]pyrimidine product in each case, which were isolated and purified by precipitation and crystallization. Chromatographic recovery from filtrates raised the total yields to 49-66%. The procedure provides a practical alternative to hitherto reported methods in which formation of multiple products was observed.",
keywords = "Ammonium chloride, Combinatorial chemistry, Imidazo[1,2-a]pyrimidine, Toluene, Ugi reaction",
author = "Parchinsky, {Vladislav Z.} and Olga Shuvalova and Olga Ushakova and Kravchenko, {Dmitry V.} and Mikhail Krasavin",
year = "2006",
month = feb,
day = "6",
doi = "10.1016/j.tetlet.2005.11.152",
language = "English",
volume = "47",
pages = "947--951",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier",
number = "6",

}

RIS

TY - JOUR

T1 - Multi-component reactions between 2-aminopyrimidine, aldehydes and isonitriles

T2 - The use of a nonpolar solvent suppresses formation of multiple products

AU - Parchinsky, Vladislav Z.

AU - Shuvalova, Olga

AU - Ushakova, Olga

AU - Kravchenko, Dmitry V.

AU - Krasavin, Mikhail

PY - 2006/2/6

Y1 - 2006/2/6

N2 - A reliable and convenient protocol for MCRs between 2-aminopyrimidine, aldehydes and isonitriles is described. Toluene was chosen as the reaction solvent based on mechanistic reasoning. The product mixtures were found to contain a single imidazo[1,2-a]pyrimidine product in each case, which were isolated and purified by precipitation and crystallization. Chromatographic recovery from filtrates raised the total yields to 49-66%. The procedure provides a practical alternative to hitherto reported methods in which formation of multiple products was observed.

AB - A reliable and convenient protocol for MCRs between 2-aminopyrimidine, aldehydes and isonitriles is described. Toluene was chosen as the reaction solvent based on mechanistic reasoning. The product mixtures were found to contain a single imidazo[1,2-a]pyrimidine product in each case, which were isolated and purified by precipitation and crystallization. Chromatographic recovery from filtrates raised the total yields to 49-66%. The procedure provides a practical alternative to hitherto reported methods in which formation of multiple products was observed.

KW - Ammonium chloride

KW - Combinatorial chemistry

KW - Imidazo[1,2-a]pyrimidine

KW - Toluene

KW - Ugi reaction

UR - http://www.scopus.com/inward/record.url?scp=30344436379&partnerID=8YFLogxK

U2 - 10.1016/j.tetlet.2005.11.152

DO - 10.1016/j.tetlet.2005.11.152

M3 - Article

AN - SCOPUS:30344436379

VL - 47

SP - 947

EP - 951

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 6

ER -

ID: 97905470