TY - JOUR

T1 - Monolithic methacrylate polymeric sorbents

T2 - Development of methods for chemical modification of the surface for the subsequent bioaffine functionalization

AU - Sinitsyna, E. S.

AU - Vlasova, E. N.

AU - Vlakh, E. G.

AU - Tennikova, T. B.

PY - 2008/8/1

Y1 - 2008/8/1

N2 - Copolymers containing aldehyde, succinimidyl carbonate, and imidazolecarbamate groups were prepared by polymer-analogous transformations of epoxy groups of a macroporous monolithic polymeric support derived from glycidyl methacrylate and ethylene glycol dimethacyrlate. The effect of certain parameters on the course of the copolymer modification and immobilization of a protein on the surface of the polymeric support was studied. The possibility of using the matrices obtained for development of biorecognizing systems was examined.

AB - Copolymers containing aldehyde, succinimidyl carbonate, and imidazolecarbamate groups were prepared by polymer-analogous transformations of epoxy groups of a macroporous monolithic polymeric support derived from glycidyl methacrylate and ethylene glycol dimethacyrlate. The effect of certain parameters on the course of the copolymer modification and immobilization of a protein on the surface of the polymeric support was studied. The possibility of using the matrices obtained for development of biorecognizing systems was examined.

UR - http://www.scopus.com/inward/record.url?scp=52949126730&partnerID=8YFLogxK

U2 - 10.1134/S1070427208080168

DO - 10.1134/S1070427208080168

M3 - Article

AN - SCOPUS:52949126730

VL - 81

SP - 1403

EP - 1409

JO - Russian Journal of Applied Chemistry

JF - Russian Journal of Applied Chemistry

SN - 1070-4272

IS - 8

ER -