Standard

Monoclonal antibodies against human IgG subclasses : Epitope specificity and immunoassay applications. / Klimovich, V. B.; Samoilovich, M. P.; Krutetskaya, I. Yu; Pashkova, S. F.

в: Immunologiya, № 3, 1998, стр. 31-34.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Klimovich, VB, Samoilovich, MP, Krutetskaya, IY & Pashkova, SF 1998, 'Monoclonal antibodies against human IgG subclasses: Epitope specificity and immunoassay applications', Immunologiya, № 3, стр. 31-34.

APA

Klimovich, V. B., Samoilovich, M. P., Krutetskaya, I. Y., & Pashkova, S. F. (1998). Monoclonal antibodies against human IgG subclasses: Epitope specificity and immunoassay applications. Immunologiya, (3), 31-34.

Vancouver

Klimovich VB, Samoilovich MP, Krutetskaya IY, Pashkova SF. Monoclonal antibodies against human IgG subclasses: Epitope specificity and immunoassay applications. Immunologiya. 1998;(3):31-34.

Author

Klimovich, V. B. ; Samoilovich, M. P. ; Krutetskaya, I. Yu ; Pashkova, S. F. / Monoclonal antibodies against human IgG subclasses : Epitope specificity and immunoassay applications. в: Immunologiya. 1998 ; № 3. стр. 31-34.

BibTeX

@article{b600fe094f1b487bba85574359abb8d7,
title = "Monoclonal antibodies against human IgG subclasses: Epitope specificity and immunoassay applications",
abstract = "The aim of the study was to investigate epitope specificity of new monoclonal antibodies (MAb) against human IgG1, IgG2, IgG3, IgG4 and to estimate some models of their application. The topography of subclass- specific epitopes on IgG molecules was investigated using a set of peroxidase-labelled MAb under study and unlabelled MAb with known epitope specificity by means of competitive inhibition test. The scheme of class and subclass-specific IgG epitopes location is presented. Combinations of MAb directed to spatially distant epitopes for two-site immunometric quantification of IgG subclasses were selected. They consisted of pairs of subclass-specific MAb used as capture reagents and complementary enzyme- labelled class-specific developing MAb. Labelled subclass-specific MAb are shown to be suitable also for immunosorbent assay of sub-isotypic patterns of antibody response against foreign and auto-antigens.",
author = "Klimovich, {V. B.} and Samoilovich, {M. P.} and Krutetskaya, {I. Yu} and Pashkova, {S. F.}",
year = "1998",
language = "English",
pages = "31--34",
journal = "ИММУНОЛОГИЯ",
issn = "0206-4952",
publisher = "Медицина",
number = "3",

}

RIS

TY - JOUR

T1 - Monoclonal antibodies against human IgG subclasses

T2 - Epitope specificity and immunoassay applications

AU - Klimovich, V. B.

AU - Samoilovich, M. P.

AU - Krutetskaya, I. Yu

AU - Pashkova, S. F.

PY - 1998

Y1 - 1998

N2 - The aim of the study was to investigate epitope specificity of new monoclonal antibodies (MAb) against human IgG1, IgG2, IgG3, IgG4 and to estimate some models of their application. The topography of subclass- specific epitopes on IgG molecules was investigated using a set of peroxidase-labelled MAb under study and unlabelled MAb with known epitope specificity by means of competitive inhibition test. The scheme of class and subclass-specific IgG epitopes location is presented. Combinations of MAb directed to spatially distant epitopes for two-site immunometric quantification of IgG subclasses were selected. They consisted of pairs of subclass-specific MAb used as capture reagents and complementary enzyme- labelled class-specific developing MAb. Labelled subclass-specific MAb are shown to be suitable also for immunosorbent assay of sub-isotypic patterns of antibody response against foreign and auto-antigens.

AB - The aim of the study was to investigate epitope specificity of new monoclonal antibodies (MAb) against human IgG1, IgG2, IgG3, IgG4 and to estimate some models of their application. The topography of subclass- specific epitopes on IgG molecules was investigated using a set of peroxidase-labelled MAb under study and unlabelled MAb with known epitope specificity by means of competitive inhibition test. The scheme of class and subclass-specific IgG epitopes location is presented. Combinations of MAb directed to spatially distant epitopes for two-site immunometric quantification of IgG subclasses were selected. They consisted of pairs of subclass-specific MAb used as capture reagents and complementary enzyme- labelled class-specific developing MAb. Labelled subclass-specific MAb are shown to be suitable also for immunosorbent assay of sub-isotypic patterns of antibody response against foreign and auto-antigens.

UR - http://www.scopus.com/inward/record.url?scp=0031858496&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0031858496

SP - 31

EP - 34

JO - ИММУНОЛОГИЯ

JF - ИММУНОЛОГИЯ

SN - 0206-4952

IS - 3

ER -

ID: 89781047