Standard

Modified intraoperative PTH assay for diagnostics of multiglandular disease. / Sleptsov, Ilya V.; Chernikov, R.A.; Novokshonov, K.Y.; Karelina, Y.V.; Makarin, V.A.; Semenov, A.A.; Timofeeva, N.I.; Uspenskaya, A.A.; Chinchuk, I.K.; Malyugov, Y.N.; Fedorov, E.A.; Fedotov, Y.N.; Bubnov, A.N.

в: Langenbeck's Archives of Surgery, Том 400, 2015.

Результаты исследований: Научные публикации в периодических изданияхтезисыРецензирование

Harvard

Sleptsov, IV, Chernikov, RA, Novokshonov, KY, Karelina, YV, Makarin, VA, Semenov, AA, Timofeeva, NI, Uspenskaya, AA, Chinchuk, IK, Malyugov, YN, Fedorov, EA, Fedotov, YN & Bubnov, AN 2015, 'Modified intraoperative PTH assay for diagnostics of multiglandular disease', Langenbeck's Archives of Surgery, Том. 400. https://doi.org/10.1007/s00423-015-1299-6

APA

Sleptsov, I. V., Chernikov, R. A., Novokshonov, K. Y., Karelina, Y. V., Makarin, V. A., Semenov, A. A., Timofeeva, N. I., Uspenskaya, A. A., Chinchuk, I. K., Malyugov, Y. N., Fedorov, E. A., Fedotov, Y. N., & Bubnov, A. N. (2015). Modified intraoperative PTH assay for diagnostics of multiglandular disease. Langenbeck's Archives of Surgery, 400. https://doi.org/10.1007/s00423-015-1299-6

Vancouver

Author

Sleptsov, Ilya V. ; Chernikov, R.A. ; Novokshonov, K.Y. ; Karelina, Y.V. ; Makarin, V.A. ; Semenov, A.A. ; Timofeeva, N.I. ; Uspenskaya, A.A. ; Chinchuk, I.K. ; Malyugov, Y.N. ; Fedorov, E.A. ; Fedotov, Y.N. ; Bubnov, A.N. / Modified intraoperative PTH assay for diagnostics of multiglandular disease. в: Langenbeck's Archives of Surgery. 2015 ; Том 400.

BibTeX

@article{e1f0d6e2a63943aebbf4f587a631a005,
title = "Modified intraoperative PTH assay for diagnostics of multiglandular disease",
abstract = "Background: To estimate the efficacy and cost of the modified immunochemiluminescent quick PTH assay using the decreased reagents incubation time. Methods: Three hundred twenty-six patients with primary hyperparathyroidism were operated in 2011–2012 using the modified PTH assay. In all the cases, selective parathyroidectomy was performed with PTH testing in three time points: pre-incision, pre-excision, and 10 min after adenoma removal. Blood samples were estimated by two methods: standard PTH assay (DiaSorin Liaison, Italy, time to result 25 min) and modified assay (incubation time decreased from 20 to 10 min, total time to result 15 min). In a modified test, the analyzer algorithm was changed to stop the incubation phase at 10 min without the full conjugation of the reagents and proceed to a washing phase and then to a reading phase. Results: False positive and false negative results were revealed in 1.2 and 11.4 % of cases using modified test and 50 % drop cut-off level. With 40 % drop cut-off level, the",
author = "Sleptsov, {Ilya V.} and R.A. Chernikov and K.Y. Novokshonov and Y.V. Karelina and V.A. Makarin and A.A. Semenov and N.I. Timofeeva and A.A. Uspenskaya and I.K. Chinchuk and Y.N. Malyugov and E.A. Fedorov and Y.N. Fedotov and A.N. Bubnov",
year = "2015",
doi = "10.1007/s00423-015-1299-6",
language = "English",
volume = "400",
journal = "Langenbeck's Archives of Surgery",
issn = "1435-2443",
publisher = "Springer Nature",

}

RIS

TY - JOUR

T1 - Modified intraoperative PTH assay for diagnostics of multiglandular disease

AU - Sleptsov, Ilya V.

AU - Chernikov, R.A.

AU - Novokshonov, K.Y.

AU - Karelina, Y.V.

AU - Makarin, V.A.

AU - Semenov, A.A.

AU - Timofeeva, N.I.

AU - Uspenskaya, A.A.

AU - Chinchuk, I.K.

AU - Malyugov, Y.N.

AU - Fedorov, E.A.

AU - Fedotov, Y.N.

AU - Bubnov, A.N.

PY - 2015

Y1 - 2015

N2 - Background: To estimate the efficacy and cost of the modified immunochemiluminescent quick PTH assay using the decreased reagents incubation time. Methods: Three hundred twenty-six patients with primary hyperparathyroidism were operated in 2011–2012 using the modified PTH assay. In all the cases, selective parathyroidectomy was performed with PTH testing in three time points: pre-incision, pre-excision, and 10 min after adenoma removal. Blood samples were estimated by two methods: standard PTH assay (DiaSorin Liaison, Italy, time to result 25 min) and modified assay (incubation time decreased from 20 to 10 min, total time to result 15 min). In a modified test, the analyzer algorithm was changed to stop the incubation phase at 10 min without the full conjugation of the reagents and proceed to a washing phase and then to a reading phase. Results: False positive and false negative results were revealed in 1.2 and 11.4 % of cases using modified test and 50 % drop cut-off level. With 40 % drop cut-off level, the

AB - Background: To estimate the efficacy and cost of the modified immunochemiluminescent quick PTH assay using the decreased reagents incubation time. Methods: Three hundred twenty-six patients with primary hyperparathyroidism were operated in 2011–2012 using the modified PTH assay. In all the cases, selective parathyroidectomy was performed with PTH testing in three time points: pre-incision, pre-excision, and 10 min after adenoma removal. Blood samples were estimated by two methods: standard PTH assay (DiaSorin Liaison, Italy, time to result 25 min) and modified assay (incubation time decreased from 20 to 10 min, total time to result 15 min). In a modified test, the analyzer algorithm was changed to stop the incubation phase at 10 min without the full conjugation of the reagents and proceed to a washing phase and then to a reading phase. Results: False positive and false negative results were revealed in 1.2 and 11.4 % of cases using modified test and 50 % drop cut-off level. With 40 % drop cut-off level, the

U2 - 10.1007/s00423-015-1299-6

DO - 10.1007/s00423-015-1299-6

M3 - Meeting Abstract

VL - 400

JO - Langenbeck's Archives of Surgery

JF - Langenbeck's Archives of Surgery

SN - 1435-2443

ER -

ID: 117805633