Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Modification of fullerene with amino acids as a method for obtaining biocompatible materials with a protective effect. / Шаройко, Владимир Владимирович; Шемчук, Ольга Сергеевна; Мещеряков, А.А.; Андоскин, Павел; Петров, Андрей Витальевич; Румянцев, Андрей Михайлович; Самбук, Елена Викторовна; Майстренко, Дмитрий Николаевич; Молчанов, Олег Евгеньевич; Мурин, Игорь Васильевич; Чарыков, Николай Александрович ; Семёнов, Константин Николаевич.
в: Fullerenes Nanotubes and Carbon Nanostructures, Том 32, № 7, 19.07.2024, стр. 631-639.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Modification of fullerene with amino acids as a method for obtaining biocompatible materials with a protective effect
AU - Шаройко, Владимир Владимирович
AU - Шемчук, Ольга Сергеевна
AU - Мещеряков, А.А.
AU - Андоскин, Павел
AU - Петров, Андрей Витальевич
AU - Румянцев, Андрей Михайлович
AU - Самбук, Елена Викторовна
AU - Майстренко, Дмитрий Николаевич
AU - Молчанов, Олег Евгеньевич
AU - Мурин, Игорь Васильевич
AU - Чарыков, Николай Александрович
AU - Семёнов, Константин Николаевич
PY - 2024/7/19
Y1 - 2024/7/19
N2 - Fullerenes and their derivatives have great potential for use as materials for medicine and biology. Fullerenes can enter into various reactions due to the presence of double bonds in their structure; it has also been repeatedly noted in the literature that the molecules have antiradical activity, biocompatibility, the ability to pass through biobarriers and immobilize various active molecules. In this work, a water-soluble adduct of C60 fullerene with glycine was synthesized, its physicochemical properties, biocompatibility were studied, and a protective effects toward collagen photodegradation as well as in the model reaction of human serum albumin glycation was shown.
AB - Fullerenes and their derivatives have great potential for use as materials for medicine and biology. Fullerenes can enter into various reactions due to the presence of double bonds in their structure; it has also been repeatedly noted in the literature that the molecules have antiradical activity, biocompatibility, the ability to pass through biobarriers and immobilize various active molecules. In this work, a water-soluble adduct of C60 fullerene with glycine was synthesized, its physicochemical properties, biocompatibility were studied, and a protective effects toward collagen photodegradation as well as in the model reaction of human serum albumin glycation was shown.
U2 - 10.1080/1536383x.2023.2291484
DO - 10.1080/1536383x.2023.2291484
M3 - Article
VL - 32
SP - 631
EP - 639
JO - Fullerenes Nanotubes and Carbon Nanostructures
JF - Fullerenes Nanotubes and Carbon Nanostructures
SN - 1536-383X
IS - 7
ER -
ID: 122275599