An important component of improving the healthcare system is providing medical institutions with highly qualified personnel. In the era of evidence-based medicine, clinical guidelines developed by the expert community and approved by regulatory authorities are the cornerstone of maintaining the knowledge and skills of medical personnel at a high level. In modern medicine, new data are accumulating very quickly, which requires regular changes in the algorithms for managing specialized patients. Frequent updating of clinical guidelines and their increasing importance as a document regulating the provision of medical care to patients with various diseases necessitate the intensification of additional professional education of doctors. Doctors’ awareness of the current provisions of clinical guidelines and readiness to implement them in everyday practice is an important condition for the compliance of real medical care with modern requirements. Under the conditions of the system of continuous medical education, the programs for improving the skills of doctors should be constantly improved. The article discusses the methodology for updating educational programs based on the analysis of the results of an anonymous survey of doctors on the main aspects of the current clinical guidelines. Identification of questions, the answers to which turn out to be incorrect more often than others, and quantitative analysis of the distribution of incorrect answers allow to correct programs in order to achieve a higher level of knowledge of trainees in the most difficult sections of clinical guidelines. Information about the changes that were made to the advanced training programs for doctors in the diagnosis and treatment of cardiovascular diseases on the basis of the data obtained during the questionnaire is presented. It is expected that the discussed methodology for updating the advanced training programs for doctors will help to improve the provision of the needs of modern healthcare for highly qualified personnel.