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MetaMiner : A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities. / Cao, Liu; Gurevich, Alexey; Alexander, Kelsey L.; Naman, C. Benjamin; Leão, Tiago; Glukhov, Evgenia; Luzzatto-Knaan, Tal; Vargas, Fernando; Quinn, Robby; Bouslimani, Amina; Nothias, Louis Felix; Singh, Nitin K.; Sanders, Jon G.; Benitez, Rodolfo A.S.; Thompson, Luke R.; Hamid, Md Nafiz; Morton, James T.; Mikheenko, Alla; Shlemov, Alexander; Korobeynikov, Anton; Friedberg, Iddo; Knight, Rob; Venkateswaran, Kasthuri; Gerwick, William H.; Gerwick, Lena; Dorrestein, Pieter C.; Pevzner, Pavel A.; Mohimani, Hosein.
в:
Cell Systems, Том 9, № 6, 18.12.2019, стр. 600-608.e4.
Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Harvard
Cao, L
, Gurevich, A, Alexander, KL, Naman, CB, Leão, T, Glukhov, E, Luzzatto-Knaan, T, Vargas, F, Quinn, R, Bouslimani, A, Nothias, LF, Singh, NK, Sanders, JG, Benitez, RAS, Thompson, LR, Hamid, MN, Morton, JT
, Mikheenko, A, Shlemov, A, Korobeynikov, A, Friedberg, I, Knight, R, Venkateswaran, K, Gerwick, WH, Gerwick, L, Dorrestein, PC, Pevzner, PA & Mohimani, H 2019, '
MetaMiner: A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities',
Cell Systems, Том. 9, № 6, стр. 600-608.e4.
https://doi.org/10.1016/j.cels.2019.09.004,
https://doi.org/10.1016/j.cels.2019.09.004APA
Cao, L.
, Gurevich, A., Alexander, K. L., Naman, C. B., Leão, T., Glukhov, E., Luzzatto-Knaan, T., Vargas, F., Quinn, R., Bouslimani, A., Nothias, L. F., Singh, N. K., Sanders, J. G., Benitez, R. A. S., Thompson, L. R., Hamid, M. N., Morton, J. T.
, Mikheenko, A., Shlemov, A., ... Mohimani, H. (2019).
MetaMiner: A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities.
Cell Systems,
9(6), 600-608.e4.
https://doi.org/10.1016/j.cels.2019.09.004,
https://doi.org/10.1016/j.cels.2019.09.004Vancouver
Author
Cao, Liu
; Gurevich, Alexey ; Alexander, Kelsey L. ; Naman, C. Benjamin ; Leão, Tiago ; Glukhov, Evgenia ; Luzzatto-Knaan, Tal ; Vargas, Fernando ; Quinn, Robby ; Bouslimani, Amina ; Nothias, Louis Felix ; Singh, Nitin K. ; Sanders, Jon G. ; Benitez, Rodolfo A.S. ; Thompson, Luke R. ; Hamid, Md Nafiz ; Morton, James T.
; Mikheenko, Alla ; Shlemov, Alexander ; Korobeynikov, Anton ; Friedberg, Iddo ; Knight, Rob ; Venkateswaran, Kasthuri ; Gerwick, William H. ; Gerwick, Lena ; Dorrestein, Pieter C. ; Pevzner, Pavel A. ; Mohimani, Hosein. /
MetaMiner : A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities. в:
Cell Systems. 2019 ; Том 9, № 6. стр. 600-608.e4.
BibTeX
@article{80967709b6fa4a3ba5a099930e724575,
title = "MetaMiner: A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities",
abstract = "We have developed an efficient method for discovering ribosomally synthesized and post-translationally modified peptides with unknown post-translational modifications from microbial communities through the database search of mass spectra against peptides predicted by genome or metagenome mining. Searching eight datasets collected from various environments—including human microbiome, marine cyanobacteria, and International Space Station—resulted in the discovery of seven unknown RiPPs.",
keywords = "computational mass spectrometry, metagenomics, microbial metabolites, natural products discovery, ribosomally synthesized and post-translationally modified peptides",
author = "Liu Cao and Alexey Gurevich and Alexander, {Kelsey L.} and Naman, {C. Benjamin} and Tiago Le{\~a}o and Evgenia Glukhov and Tal Luzzatto-Knaan and Fernando Vargas and Robby Quinn and Amina Bouslimani and Nothias, {Louis Felix} and Singh, {Nitin K.} and Sanders, {Jon G.} and Benitez, {Rodolfo A.S.} and Thompson, {Luke R.} and Hamid, {Md Nafiz} and Morton, {James T.} and Alla Mikheenko and Alexander Shlemov and Anton Korobeynikov and Iddo Friedberg and Rob Knight and Kasthuri Venkateswaran and Gerwick, {William H.} and Lena Gerwick and Dorrestein, {Pieter C.} and Pevzner, {Pavel A.} and Hosein Mohimani",
year = "2019",
month = dec,
day = "18",
doi = "10.1016/j.cels.2019.09.004",
language = "English",
volume = "9",
pages = "600--608.e4",
journal = "Cell Systems",
issn = "2405-4712",
publisher = "Cell Press",
number = "6",
}
RIS
TY - JOUR
T1 - MetaMiner
T2 - A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities
AU - Cao, Liu
AU - Gurevich, Alexey
AU - Alexander, Kelsey L.
AU - Naman, C. Benjamin
AU - Leão, Tiago
AU - Glukhov, Evgenia
AU - Luzzatto-Knaan, Tal
AU - Vargas, Fernando
AU - Quinn, Robby
AU - Bouslimani, Amina
AU - Nothias, Louis Felix
AU - Singh, Nitin K.
AU - Sanders, Jon G.
AU - Benitez, Rodolfo A.S.
AU - Thompson, Luke R.
AU - Hamid, Md Nafiz
AU - Morton, James T.
AU - Mikheenko, Alla
AU - Shlemov, Alexander
AU - Korobeynikov, Anton
AU - Friedberg, Iddo
AU - Knight, Rob
AU - Venkateswaran, Kasthuri
AU - Gerwick, William H.
AU - Gerwick, Lena
AU - Dorrestein, Pieter C.
AU - Pevzner, Pavel A.
AU - Mohimani, Hosein
PY - 2019/12/18
Y1 - 2019/12/18
N2 - We have developed an efficient method for discovering ribosomally synthesized and post-translationally modified peptides with unknown post-translational modifications from microbial communities through the database search of mass spectra against peptides predicted by genome or metagenome mining. Searching eight datasets collected from various environments—including human microbiome, marine cyanobacteria, and International Space Station—resulted in the discovery of seven unknown RiPPs.
AB - We have developed an efficient method for discovering ribosomally synthesized and post-translationally modified peptides with unknown post-translational modifications from microbial communities through the database search of mass spectra against peptides predicted by genome or metagenome mining. Searching eight datasets collected from various environments—including human microbiome, marine cyanobacteria, and International Space Station—resulted in the discovery of seven unknown RiPPs.
KW - computational mass spectrometry
KW - metagenomics
KW - microbial metabolites
KW - natural products discovery
KW - ribosomally synthesized and post-translationally modified peptides
UR - http://www.scopus.com/inward/record.url?scp=85076261727&partnerID=8YFLogxK
UR - http://www.mendeley.com/research/metaminer-scalable-peptidogenomics-approach-discovery-ribosomal-peptide-natural-products-blind-modif
U2 - 10.1016/j.cels.2019.09.004
DO - 10.1016/j.cels.2019.09.004
M3 - Article
C2 - 31629686
VL - 9
SP - 600-608.e4
JO - Cell Systems
JF - Cell Systems
SN - 2405-4712
IS - 6
ER -
