Результаты исследований: Научные публикации в периодических изданиях › Обзорная статья › Рецензирование
Metagenomic Data Assembly – The Way of Decoding Unknown Microorganisms. / Lapidus, Alla L.; Korobeynikov, Anton I.
в: Frontiers in Microbiology, Том 12, 613791, 23.03.2021.Результаты исследований: Научные публикации в периодических изданиях › Обзорная статья › Рецензирование
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TY - JOUR
T1 - Metagenomic Data Assembly – The Way of Decoding Unknown Microorganisms
AU - Lapidus, Alla L.
AU - Korobeynikov, Anton I.
N1 - Publisher Copyright: © Copyright © 2021 Lapidus and Korobeynikov. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/3/23
Y1 - 2021/3/23
N2 - Metagenomics is a segment of conventional microbial genomics dedicated to the sequencing and analysis of combined genomic DNA of entire environmental samples. The most critical step of the metagenomic data analysis is the reconstruction of individual genes and genomes of the microorganisms in the communities using metagenomic assemblers – computational programs that put together small fragments of sequenced DNA generated by sequencing instruments. Here, we describe the challenges of metagenomic assembly, a wide spectrum of applications in which metagenomic assemblies were used to better understand the ecology and evolution of microbial ecosystems, and present one of the most efficient microbial assemblers, SPAdes that was upgraded to become applicable for metagenomics.
AB - Metagenomics is a segment of conventional microbial genomics dedicated to the sequencing and analysis of combined genomic DNA of entire environmental samples. The most critical step of the metagenomic data analysis is the reconstruction of individual genes and genomes of the microorganisms in the communities using metagenomic assemblers – computational programs that put together small fragments of sequenced DNA generated by sequencing instruments. Here, we describe the challenges of metagenomic assembly, a wide spectrum of applications in which metagenomic assemblies were used to better understand the ecology and evolution of microbial ecosystems, and present one of the most efficient microbial assemblers, SPAdes that was upgraded to become applicable for metagenomics.
KW - Metagenomics
KW - Microbiota
KW - Microbiome
KW - Genome assembly
KW - SPAdes
KW - algorithms
KW - metagenomic assembly
KW - metagenomics
KW - microbiota
UR - http://www.scopus.com/inward/record.url?scp=85103782072&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/460de301-6420-3565-b061-4ccfd01d39fc/
U2 - 10.3389/fmicb.2021.613791
DO - 10.3389/fmicb.2021.613791
M3 - Review article
AN - SCOPUS:85103782072
VL - 12
JO - Frontiers in Microbiology
JF - Frontiers in Microbiology
SN - 1664-302X
M1 - 613791
ER -
ID: 75242360