TY - JOUR

T1 - Melamine–Barbiturate Supramolecular Assembly as a pH-Dependent Organic Radical Trap Material

AU - Shilovskikh, Vladimir V.

AU - Timralieva, Alexandra A.

AU - Nesterov, Pavel V.

AU - Novikov, Alexander S.

AU - Sitnikov, Petr A.

AU - Konstantinova, Elizaveta A.

AU - Kokorin, Alexander I.

AU - Skorb, Ekaterina V.

N1 - Funding Information: This work was supported by the Ministry of Science and Higher Education of the Russian Federation, goszadanie no. 2019‐1075. ITMO Fellowship and Professorship Program is acknowledged for infrastructural support. Authors are grateful to Prof. A. Kh. Vorob′ev (Chemistry Department, M.V. Lomonosov Moscow State University) for providing his software package. Authors are grateful to P. V. Khvorov (South Urals Federal Research Center of Mineralogy and Geoecology UB RAS) for powder X‐ray diffraction data.

PY - 2020/12/15

Y1 - 2020/12/15

N2 - In the last two decades, a large number of self-assembled materials were synthesized and they have already found their way into large-scale industry and science. Hydrogen-bond-based supramolecular adducts are found to have unique properties and to be perfect host structures for trapping target molecules or ions. Such chemical systems are believed to resemble living matter and can substitute a living cell in a number of cases. Herein, a report on an organic material based on supramolecular assembly of barbituric acid and melamine is presented. Surprisingly, the structure is found to host and stabilize radicals under mild conditions allowing its use for biological applications. The number of free radicals is found to be easily tuned by changing the pH of the environment and it increases when exposed to light up to a saturation level. We describe a preparation method as well as stability properties of melamine–barbiturate self-assembly, potentiometric titration, and hydrogen ions adsorption data and EPR spectra concerning the composite.

AB - In the last two decades, a large number of self-assembled materials were synthesized and they have already found their way into large-scale industry and science. Hydrogen-bond-based supramolecular adducts are found to have unique properties and to be perfect host structures for trapping target molecules or ions. Such chemical systems are believed to resemble living matter and can substitute a living cell in a number of cases. Herein, a report on an organic material based on supramolecular assembly of barbituric acid and melamine is presented. Surprisingly, the structure is found to host and stabilize radicals under mild conditions allowing its use for biological applications. The number of free radicals is found to be easily tuned by changing the pH of the environment and it increases when exposed to light up to a saturation level. We describe a preparation method as well as stability properties of melamine–barbiturate self-assembly, potentiometric titration, and hydrogen ions adsorption data and EPR spectra concerning the composite.

KW - electron paramagnetic resonance

KW - hydrogen bonds

KW - radical trap

KW - self-assembly

KW - supramolecular chemistry

KW - OXYGEN

KW - NONCOVALENT SYNTHESIS

KW - SPIN TRAPS

KW - SURFACE

UR - http://www.scopus.com/inward/record.url?scp=85097008906&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/ab3f5603-1d68-37d8-ab1b-fbcefa3b5c67/

U2 - 10.1002/chem.202002947

DO - 10.1002/chem.202002947

M3 - Article

VL - 26

SP - 16603

EP - 16610

JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

SN - 0947-6539

IS - 70

ER -