The development of a supersonic gas flow over a wedge in the process of interaction of a plane shock wave with the wedge was mathematically simulated on the basis of solution of the Euler equations for the nonstationary flow of a compressible inviscid gas in a two-dimensional space with regard for the high-temperature effects of ionization and dissociation of the gas arising in the gas flow due to the balanced chemical reactions proceeding in it. The results of solution of the problem on the supersonic gas flow over a wedge within the framework of the perfect-gas and real-gas models were compared. The influence of the high-temperature effects in this flow on its characteristics and the angle of inclination of a shock wave in it to the wedge was investigated.