A mathematical model for the bending of a plastically anisotropic beam simply supported at both ends and subjected to a constant moment is considered. A differential equation with variable coefficients is derived for the beam curvature. The yield points of the beam material under tension and compression are assumed to be known. The elastoplastic bending of the beam with allowance for the strength-different (SD) effect is considered. The classical Bernoulli–Euler beam theory and the ideal plasticity model are used construct the mathematical model, and the problem is solved analytically. The solutions obtained for a classical isotropic beam and an SD beam are compared, and the contribution of the SD effect is analyzed. The problem is solved completely, and its results can be used to study bending under different loading.